禽大肠杆菌病的非抗生素物质防控研究进展  

Research Advances on Prevention and Control of Avian Colibacillosis with Non-Antibiotic Substances

作　　者：李鹏飞 黄嘉 毕睿晨 王忠 LI Pengfei;HUANG Jia;BI Ruichen;WANG Zhong(State Key Laboratory of Animal Nutrition and Feeding,College of Animal Science and Technology,China Agricultural University,Beijing 100193,China)

机构地区：[1]中国农业大学动物科学技术学院,畜禽营养与饲养全国重点实验室,北京100193

出　　处：《动物营养学报》2024年第8期4809-4822,共14页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金项目(31220774)。

摘　　要：禽大肠杆菌病是危害养鸡业发展的主要细菌性传染病之一,给家禽产业带来了巨大的经济损失。抗生素在预防和治疗禽大肠杆菌病中有重要作用。然而,随着世界范围内在养鸡领域治疗性抗生素限用和饲用抗生素禁用措施的实施,禽大肠杆菌病的发病率在全球范围内呈上升趋势,对家禽生长与健康造成严重威胁。因此,迫切需要研发新的技术和产品代替抗生素来预防和控制禽大肠杆菌病。本文首先简介了禽大肠杆菌病的危害,然后重点综述了饲用抗生素替代物在预防和控制禽致病性大肠杆菌感染中的效果和作用机制,为应用非抗生素物质预防禽大肠杆菌病提供参考,为研发防控禽大肠杆菌病的新型非抗生素物质的提供借鉴。Avian colibacillosis is one of the main bacterial infectious diseases that seriously influences the health,growth and production of poultry,which brings huge economic losses to poultry industry.Antibiotics play an important role in the prevention and treatment of avian colibacillosis.However,with the implementation of the restriction of therapeutic antibiotics and the prohibition of feeding antibiotics in chickens worldwide,the incidence of avian colibacillosis is on the rise globally,posing a serious threat to the growth and health of poultry.Therefore,there is an urgent need to develop new technologies and products to replace antibiotics for the prevention and control of avian colibacillosis.This review first introduces the risks of avian colibacillosis,and then focuses on the efficacy and mechanism of feeding antibiotic substitutes in the prevention and control of avian pathogenic Escherichia coli(APEC)infection.The article will provide theoretical references for the development and application of non-antibiotic substances to prevent and control avian colibacillosis.

关 键 词：禽大肠杆菌病 禽致病性大肠杆菌 非抗生素物质 

分 类 号：S83[农业科学—畜牧学]