清热安神胶囊联合胺碘酮治疗痰火扰心型频发室早临床研究  

Clinical Study on the Combination of Qingre Anshen Capsules and Amiodarone in the Treatment of Frequent Ventricular Premature Beats of Phlegm Fire Disturbance Heart Type

作　　者：翟夏[1,2] 康启 董静 马淑慧[1,2] 王琼 李燕[1] 牛铁 ZHAI Xia;KANG Qi;DONG Jing;MA Shuhui;WANG Qiong;LI Yan;NIU Tie(Second Affiliated Hospital of Shaanxi University of Chinese Medicine,Shaanxi Xi'an 712000,China;Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Cardiovascular Diseases,Shaanxi Xi'an 712000,China)

机构地区：[1]陕西中医药大学第二附属医院,陕西西安712000 [2]陕西省中西医结合防治心血管疾病重点实验室,陕西西安712000

出　　处：《陕西中医药大学学报》2024年第5期107-112,共6页Journal of Shaanxi University of Chinese Medicine

基　　金：陕西省科技厅重点研发计划项目(2020SF-277);咸阳市重点研发计划项目(2019k02-89)。

摘　　要：目的观察清热安神胶囊联合胺碘酮治疗痰火扰心型频发室性早搏(premature ventricualr contraction,PVC)的临床疗效。方法将80例符合纳入排除标准的患者随机分成两组,对照组给予单用胺碘酮治疗,治疗组采用胺碘酮联合清热安神胶囊治疗,治疗1月后比较两组患者的检测指标和临床效果,房室大小、EF值、早搏类型、数量、形态、总心搏数、室性早搏数量等变化。结果治疗后治疗组患者心悸症状比例(16.25%vs 47.50%,P<0.05)、中医证候积分和室早负荷中位数(13.9%vs 16.4%,P<0.05)的改善程度明显优于对照组。结论联合使用胺碘酮和清热安神胶囊用于治疗PVC的临床效果明显优于单用胺碘酮治疗。Objective To observe the clinical efficacy of Qingre Anshen Capsules combined with amiodarone in the treatment of premature ventricular contractions(PVC)of phlegm fire disturbance heart type.Methods 80 patients who met the inclusion and exclusion criteria were randomly divided into two groups.The control group was treated with amiodarone alone,while the treatment group was treated with amiodarone combined with Qingre Anshen capsules.After one month of treatment,the detection indicators and clinical effects of the two groups of patients were compared,including changes in atrioventricular size,EF value,premature beat type,quantity,morphology,total heart rate,and ventricular premature beats.Results After treatment,the improvement in the proportion of palpitations(16.25%vs 47.50%,P<0.05),TCM syndrome score,and median ventricular premature load(13.9%vs 16.4%,P<0.05)in the treatment group was significantly better than that in the control group.Conclusion The clinical effect of combining amiodarone and Qingre Anshen capsules in the treatment of PVC is significantly better than using amiodarone alone.

关 键 词：频发室性早搏 清热安神胶囊 室早负荷 临床疗效 胺碘酮 

分 类 号：R541.76[医药卫生—心血管疾病]