脐带血检测对早产儿并发症预测作用的研究进展  

Progress in the study of the predictive role of umbilical cord blood testing for complications in preterm infants

作　　者：董志隆(综述) 黄华飞[3] 徐志国(审校) DONG Zhilong;HUANG Huafei;XU Zhiguo(School of Life Sciences,Nankai University,Tianjin 300074,China;Tianjin Cord Blood Bank,National Industrial Base for Stem Cell Engineering Products,Tianjin 300384,China;Department of Neonatology,Jiaxing Maternity and Child Health Hospital,Jiaxing,Zhejiang 314009,China;Department of Pharmaceutical Engineering,School of Life and Health Sciences,Huzhou College,Huzhou,Zhejiang 313000,China;Union Huadong Stem Cell and Gene Engineering Co.,Ltd.,Huzhou,Zhejiang 313000,China)

机构地区：[1]南开大学生命科学学院,天津300071 [2]国家干细胞工程产品产业基地天津市脐带血库,天津300384 [3]嘉兴市妇幼保健院新生儿科,浙江嘉兴314009 [4]湖州学院生命健康学院制药工程系,浙江湖州313000 [5]协和华东干细胞基因工程有限公司,浙江湖州313000

出　　处：《国际检验医学杂志》2024年第17期2141-2144,共4页International Journal of Laboratory Medicine

基　　金：湖州市科学技术局攻关计划工业项目(2020GG32)。

摘　　要：早产儿并发症发病率高,为新生儿健康带来严重的负面影响。然而,传统的检测方式难以满足早发现、早诊断、早治疗的临床需求。因此,发掘早产儿并发症的预测因素有着积极的临床意义。脐带血中含有各类丰富的生物标志物,且具备易获取、对婴儿无伤害等优势,是理想的检测标本。有很多研究探索了脐带血中的标志物单独或联合检测用于各类早产儿并发症的预测价值,以促进早产儿并发症的提前干预并改善疾病的预后。该文对脐带血检测用于预测各类早产儿并发症的作用进行了综述。The high incidence of complications in preterm infants has a serious negative impact on neonatal health.Therefore,the discovery of predictors of complications in preterm infants has a positive clinical value.Umbilical cord blood is rich in various biomarkers and has the advantages of easy access and no harm to the infants,making it an ideal specimen for testing.A number of studies had explored the predictive value of detecting markers in umbilical cord blood,either alone or in combination with other assays,for various types of preterm complications,in order to facilitate earlier intervention for preterm complications and to improve the prognosis of the disease.This paper reviews the recent development of cord blood testing for predicting complications in various types of preterm infants.

关 键 词：脐带血 早产儿 支气管肺发育不良 脑室内出血 

分 类 号：R722.6[医药卫生—儿科]