基于STRAW+10分期的广州地区围绝经期代谢综合征患者中医体质调查  

Investigation on Traditional Chinese Medicine Constitutions of Patients withPerimenopausal Metabolic Syndrome in Guangzhou Basedon STRAW+10 Staging

作　　者：林书馨 李莉[2] 徐宁宁 黄佳佳 蒋亚联 江玲[2] LIN Shu-Xin;LI Li;XU Ning-Ning;HUANG Jia-Jia;JIANG Ya-Lian;JIANG Ling(The First Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;Zhongshan Hospital of Traditional Chinese Medicine,Zhongshan 528400 Guangdong,China)

机构地区：[1]广州中医药大学第一临床医学院,广东广州510405 [2]广州中医药大学第一附属医院,广东广州510405 [3]广州中医药大学,广东广州510405 [4]中山市中医院,广东中山528400

出　　处：《广州中医药大学学报》2024年第9期2295-2301,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中医药局科研项目(编号:20212063)。

摘　　要：【目的】基于生殖衰老分期(STRAW)+10调查广州地区围绝经期代谢综合征患者的中医体质类型分布,为围绝经期代谢综合征患者提供中医体质调养理论依据。【方法】根据代谢综合征的诊断标准,纳入围绝经期代谢综合征患者共90例,根据STRAW+10分期标准分为绝经过渡早期(-2期)组49例、绝经过渡晚期(-1期)组24例、绝经后期早期(+la期)组17例。采用《中医体质分类与判定标准》对所有调查对象进行中医体质调查,同时采用焦虑自评量表(SAS)及抑郁自评量表(SDS)进行焦虑抑郁评分,分析不同STRAW+10分期患者的中医体质类型分布,比较不同STRAW+10分期患者的SAS、SDS评分情况。【结果】(1)绝经过渡早期(-2期)组的最主要中医体质类型中,出现频次最高的中医体质为阳虚质14例(29.79%),其次为平和质10例(21.28%),再次之为阴虚质和血瘀质各6例(12.76%);绝经过渡晚期(-1期)组的最主要中医体质类型中,出现频次最高的中医体质为阳虚质6例(25.00%),其次为平和质和血瘀质各4例(16.66%),再次之为气虚质和痰湿质各3例(12.50%);绝经后期早期(+la期)组的最主要中医体质类型中,出现频次最高的中医体质为阳虚质7例(46.67%),其次为平和质、痰湿质、血瘀质各2例(13.33%),再次之为气虚质、气郁质各1例(6.67%)。(2)绝经过渡早期(-2期)患者的SAS评分和SDS评分分别为(34.55±7.46)、(35.55±10.61)分,均高于绝经过渡晚期(-1期)患者的(33.83±7.73)、(35.46±11.35)分和绝经后期早期(+la期)患者的(35.65±8.67)、(36.59±12.07)分,且均高于总体平均水平。【结论】围绝经期代谢综合征患者的中医体质以阳虚质为主,平和质随着分期的进展逐渐减少,而偏颇体质从阴虚质、血瘀质逐渐转变为气虚质、痰湿质,再到痰湿质、血瘀质;随着分期进展,围绝经期代谢综合征患者本虚更虚而标实之邪也在加重。Objective To investigate the distribution of traditional Chinese medicine(TCM)constitution types in patients with perimenopause metabolic syndrome in Guangzhou based on the Stages of Reproductive Aging Workshop+10(STRAW+10),so as to provide a theoretical basis for TCM constitution regulation for patients with PMS.Methods According to the diagnostic criteria of metabolic syndrome,a total of 90 patients with PMS were included.Based on the STRAW+10 staging criteria,the PMS patients were divided into early perimenopause group(-2 phase of STRAW+10,49 cases),late perimenopause group(-1 phase of STRAW+10,24 cases),and early postmenopausal group(+la phase of STRAW+10,17 cases).Traditional Chinese Medicine Constitution Classification and Distinguishing Criteria were used to identify the TCM constitution types of all the subjects.At the same time,the Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS)were used for scoring anxiety and depression.The distribution of TCM constitution types in patients with different STRAW+10 stages was analyzed,and the SAS and SDS scores of patients with different STRAW+10 stages were compared.Results(1)The primary TCM constitution types in the early perimenopause group(-2 phase of STRAW+10)were yang deficiency constitution(14 cases,29.79%),balanced constitution(10 cases,21.28%),yin deficiency constitution(six cases,12.76%)and blood stasis constitution(six cases,12.76%).In the late perimenopause group(-1 phase of STRAW+10),the primary TCM constitution types were yang deficiency constitution(six cases,25.00%),balanced constitution(four cases,16.66%),blood stasis constitution(four cases,16.66%),qi deficiency constitution(three cases,12.50%)and phlegm-damp constitution(three cases,12.50%).In the early postmenopausal group(+la phase of STRAW+10),the primary TCM constitution types were yang deficiency constitution(seven cases,46.67%),balanced constitution(two cases,13.33%),phlegm-damp constitution(two cases,13.33%),blood stasis constitution(two cases,13.33%),qi deficiency constitut

关 键 词：STRAW+10分期 围绝经期 代谢综合征 中医体质 偏颇体质 阳虚质 广州地区 

分 类 号：R271.29[医药卫生—中医妇科学]