急诊床边血液灌流对急性有机磷农药中毒患者治愈率、并发症以及炎性因子水平的影响  

The Impact of Bedside Hemoperfusion on Cure Rate,Complications,and Inflammatory Factor Levels in Patients with Acute Organophosphorus Pesticide Poisoning in the Emergency Department

作　　者：郑国山 ZHENG Guoshan(Zhangzhou Hospital Emergency Department,Zhangzhou 363000,China)

机构地区：[1]漳州市医院急诊科,福建漳州363000

出　　处：《中华灾害救援医学》2024年第6期653-655,659,共4页Chinese Journal of Disaster Medicine

摘　　要：目的探究在对急性有机磷农药中毒患者治疗时开展急诊床边血液灌流治疗对患者治愈率、并发症以及炎性因子水平的影响。方法选择在2021年4月至2023年12月漳州市医院急诊科急诊收治急性有机磷农药中毒患者80例,按照数字表法随机分为对照组和观察组,每组各40例,对照组开展常规急救,观察组在常规救治层面上开展急诊床边血液灌流治疗。针对患者治愈率、并发症以及炎性因子水平变化情况进行研究。结果观察组治愈率较对照组显著增高(P<0.05)。观察组胆碱酯酶水平显著高于对照组,苏醒时间显著短于对照组(P<0.05)。治疗期间观察组并发症发生率显著低于对照组(P<0.05)。治疗后观察组炎性因子水平显著低于对照组(P<0.05)。两组患者肾上腺素和去甲肾上腺素水平治疗前无显著差异(P>0.05),治疗后观察组显著低于对照组(P<0.05)。结论在对急性有机磷农药中毒患者治疗过程中开展急诊床边血液灌流治疗,可以提升治愈率,降低并发症发生率,并改善体内炎性因子水平,有助于患者恢复。Objective To explore the effects of emergency bedside blood perfusion therapy on the cure rate,complications,and inflammatory factor levels in patients with acute organophosphate pesticide poisoning.Methods 80 cases of acute organophosphate pesticide poisoning patients admitted to the emergency department of Zhangzhou Hospital from April 2021 to December 2023 were selected and divided into the control group and the observation group according to the numerical table method,with 40 cases in each group.The control group received routine first aid,while the observation group received bedside blood perfusion therapy on the basis of routine treatment.We conducted research on the cure rate,complications,and changes in inflammatory factor levels of patients.Results The cure rate of the observation group was significantly higher than that of the control group(P<0.05).The level of cholinesterase in the observation group was significantly higher than that in the control group,and the recovery time was significantly shorter than that in the control group(P<0.05).The incidence of complications in the observation group during treatment was significantly lower than that in the control group(P<0.05).After treatment,the inflammatory factor levels in the observation group were significantly lower than those in the control group(P<0.05).There was no significant difference in the levels of adrenaline and noradrenaline between the two groups of patients before treatment(P>0.05),but after treatment,those of 0the observation group was significantly lower than those of the control group(P<0.05).Conclusion Emergency bedside blood perfusion therapy can improve the cure rate,reduce the incidence of complications,and improve the levels of inflammatory factors in patients with acute organophosphate pesticide poisoning,which is helpful for their recovery.

关 键 词：农药 中毒 灌流 

分 类 号：S884.96[农业科学—特种经济动物饲养]