维生素D制剂联合生活方式干预单纯性肥胖儿童对糖脂代谢的影响  

The Effect of Vitamin D Preparation Combined with Lifestyle Intervention on Glucose and Lipid Metabolism in Children with Simple Obesity

作　　者：康月雅 陈文秀 郑丽虾 KANG Yueya;CHEN Wenxiu;ZHENG Lixia(Zhangzhou Hospital in Fujian ProvinceDepartment of Child Growth and Reproduction,Zhangzhou 363100 China)

机构地区：[1]福建省漳州市医院儿童生长发育科,福建漳州363100

出　　处：《中华灾害救援医学》2024年第6期721-723,共3页Chinese Journal of Disaster Medicine

摘　　要：目的探析单纯性肥胖儿童应用维生素D制剂联合生活方式干预的效果。方法选取2018年1月至2023年12月福建省漳州市医院收治的50例单纯性肥胖儿童,以随机数字表分为对照组和观察组,每组各25例,对照组给予单纯生活方式干预,观察组在对照组基础上联合维生素D制剂干预。对两组儿童干预前后体质量、血糖、血脂水平差异进行评价。结果干预前两组儿童体质量比较差异无统计学意义(P>0.05),干预后观察组体质量降低更明显(P<0.05)。干预前两组儿童血糖水平比较差异无统计学意义(P>0.05),干预后观察组儿童血糖水平低于对照组(P<0.05)。干预前两组儿童血脂水平比较差异无统计学意义(P>0.05),干预后观察组TG、TC水平低于对照组(P<0.05)。结论为单纯性肥胖儿童展开生活方式调整基础上,联合维生素D制剂干预,对于肥胖问题和糖脂异常有更好的改善作用。Objective To explore the effect of vitamin D preparation combined with life style intervention on children with simple obesity.Methods Fifty children with simple obesity admitted to the Department of Child Growth and Development of Zhangzhou Hospital in Fujian Province from January 2018 to December 2023 were selected,and were divided into the control group and the observation group with 25 cases in each group according to a random number table.The control group was given simple lifestyle intervention,and the observation group was treated with vitamin D preparation intervention on the basis of the control group.The differences of body mass,blood glucose,and blood lipids before and after intervention were evaluated.Results There was no significant difference in body mass index between the two groups before intervention(P>0.05),but the body mass index in the observation group was lower than that in the control group after intervention(P<0.05).Before intervention,there was no statistical significance in blood glucose between the two groups(P>0.05),and after intervention,the blood glucose index of the observation group was lower than that of the control group(P<0.05).Before intervention,there was no statistical significance in blood lipid data between the two groups(P>0.05).After intervention,TG and TC indexes in the observation group were lower than those in th e control group,with statistical significance(P<0.05).Conclusion Based on lifestyle adjustment,combining vitamin D preparation can improve obesity and glycolipid abnormality in children with simple obesity.

关 键 词：肥胖症 维生素D 儿童 

分 类 号：R723.14[医药卫生—儿科]