中国肾脏移植受者移植物功能延迟恢复临床诊疗指南  

Guidelines for clinical diagnosis and treatment of delayed graft function in kidney transplant recipients in China

作　　者：中华医学会器官移植学分会 中国医疗保健国际交流促进会肾脏移植学分会 项和立[2] 王玮[3] 王建宁 徐小松 王钢[6] 薛武军[7] Branch of Organ Transplantation of Chinese Medical Association;Branch of Kidney Transplantation of China International Exchange and Promotive Association for Medical and Health Care;Xue Wujun(不详;The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]不详 [2]西安交通大学第一附属医院,西安710061 [3]首都医科大学附属北京朝阳医院 [4]山东第一医科大学第一附属医院 [5]陆军军医大学西南医院 [6]吉林大学第一医院 [7]西安交通大学第一附属医院

出　　处：《器官移植》2024年第5期684-699,共16页Organ Transplantation

基　　金：国家自然科学基金(82370802);陕西省卫生健康肾脏移植科研创新平台(2023PT-06)。

摘　　要：肾移植受者移植物功能延迟恢复是肾脏移植术后常见的早期并发症之一,是影响移植肾近期和远期存活的独立危险因素。中华医学会器官移植学分会和中国医疗保健国际交流促进会肾脏移植学分会组织国内器官移植与相关学科知名专家在《肾移植术后移植物功能延迟恢复诊疗技术规范(2019版)》的基础上经过指南范围及临床问题的确定、证据检索与筛选及推荐意见的形成等程序编写、多轮讨论,并经学会组织两轮集体审定,最终形成《中国肾脏移植受者移植物功能延迟恢复临床诊疗指南》。本指南就移植肾功能延迟恢复的概念和发生机制、危险因素、诊断、预防、治疗及免疫抑制药应用几个方面的21个临床问题提出推荐意见和推荐意见说明。目的是使肾移植术后受者移植物功能延迟恢复的诊断、预防和治疗规范化,提高肾脏移植效果,提高肾脏移植受者和移植肾近期和长期存活率,促进移植学科的发展。Delayed graft function in kidney transplant recipients is one of the common early complications after kidney transplantation,which is an independent risk factor affecting the short-term and long-term survival of renal allografts.Branch of Organ Transplantation of Chinese Medical Association and Branch of Kidney Transplantation of China International Exchange and Promotive Association for Medical and Health Care organized well-known Chinese experts in organ transplantation and related disciplines to formulate and discuss the determination of the scope and clinical problems,evidence retrieval and screening,and the formation of recommendations based on“Technical Specification for the Diagnosis and Treatment on Delayed Graft Function After Renal Transplantation(2019 edition)”.After two rounds of collective examination and approval by Chinese Medical Association and China International Exchange and Promotive Association for Medical and Health Care,“Guidelines for Clinical Diagnosis and Treatment of Delayed Graft Function in Kidney Transplant Recipients in China”was finally formulated.This guideline puts forward recommendations and explanations regarding 21 clinical problems including the concept,mechanism,risk factors,diagnosis,prevention,treatment and application of immunosuppressive drugs for delayed graft function in kidney transplant recipients,aiming to standardize the diagnosis,prevention and treatment of delayed graft function in kidney transplant recipients,enhance clinical efficacy of kidney transplantation,prolong short-term and long-term survival of kidney transplant recipients and renal allografts and promote the development of the discipline of transplantation.

关 键 词：肾脏移植 移植物功能延迟恢复 诊断 治疗 预防 免疫抑制药 

分 类 号：R617[医药卫生—外科学] R692[医药卫生—临床医学]