肾脏移植受者非结核分枝杆菌病临床诊疗指南  

Guidelines for clinical diagnosis and treatment of nontuberculous mycobacterial disease in kidney transplant recipients

作　　者：中华医学会器官移植学分会 孙其鹏 巨春蓉 罗子寰 张伟杰[5] 黄洪锋[6] 孙启全 Branch of Organ Transplantation of Chinese Medical Association;Sun Qiquan(不详;Guangdong Provincial People's Hospital,Guangzhou 510080,China)

机构地区：[1]不详 [2]广东省人民医院,广州510080 [3]广州医科大学附属第一医院 [4]广东省人民医院 [5]华中科技大学同济医学院附属同济医院 [6]浙江大学医学院附属第一医院

出　　处：《器官移植》2024年第5期712-725,共14页Organ Transplantation

基　　金：国家自然科学基金(82270783、81970650);广东省自然科学基金(2021A1515011379);广东省人民医院高层次引进人才科研基金(KY012021441、KY012021200)。

摘　　要：近年来,非结核分枝杆菌(NTM)感染呈快速增多趋势,受到广泛关注。肾脏移植受者由于免疫抑制药物等因素的影响,其NTM的感染率升高更为明显,但是由于缺乏充分的研究基础,肾脏移植术后NTM的诊治缺乏规范指引。为进一步规范我国肾脏移植受者NTM病的诊断和治疗,提高我国器官移植领域医务工作者对NTM病的认识和诊治水平,中华医学会器官移植分会组织相关专家,参考美国胸科协会及欧洲呼吸协会发布的最新版《非结核分枝杆菌病治疗指南》,我国《非结核分枝杆菌病诊断与治疗专家共识》《器官移植受者非结核分枝杆菌病临床诊疗技术规范(2019版)》等,结合肾脏移植受者的特点,进行指南制订。In recent years,the infection of nontuberculous mycobacterium(NTM)has been increasing rapidly,which captivates widespread attention.The infection rate of NTM in kidney transplant recipients is more significantly elevated due to the impact of immunosuppressive drugs and other factors.However,due to the lack of sufficient research evidence,relevant guidelines for the diagnosis and treatment of NTM after kidney transplantation are still lacking.To further standardize the diagnosis and treatment of NTM disease in kidney transplant recipients,and deepen medical practitioners'understanding and diagnosis and treatment of NTM disease in organ transplantation in China,Branch of Organ Transplantation of Chinese Medical Association organized relevant experts to formulate this guideline by referring to the latest edition of“An official ATS/IDSA statement:diagnosis,treatment,and prevention of nontuberculous mycobacterial diseases”,“Expert Consensus on the Diagnosis and Treatment of Nontuberculous Mycobacterial Disease”,and“Technical Specification for Clinical Diagnosis and Treatment of Nontuberculous Mycobacteria in Organ Transplant Recipients(2019 Edition)”,and considering the characteristics of kidney transplant recipients.

关 键 词：肾脏移植 非结核分枝杆菌 结核分枝杆菌 胞内分枝杆菌 堪萨斯分枝杆菌 鸟分枝杆菌复合体 脓肿分枝杆菌 嗜血分枝杆菌 

分 类 号：R617[医药卫生—外科学] R378[医药卫生—临床医学]