肝移植围手术期脑卒中的研究进展  

Research progress on perioperative stroke in liver transplantation

作　　者：赖曼[1] 栗光明 Lai Man;Li Guangming(Department of Intensive Care,Beijing You'an Hospital Affiliated to Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京佑安医院重症医学科,北京100069

出　　处：《器官移植》2024年第5期830-836,共7页Organ Transplantation

基　　金：北京市自然科学基金面上项目(7222096);“扬帆计划”重点培育专业-肝脏外科(ZYLX202124)。

摘　　要：肝移植是目前治疗终末期肝病的标准手段之一,随着手术技术的发展以及围手术期管理的优化,肝移植术后并发症的发生率有所下降,但围手术期神经系统并发症仍较为常见,其中脑卒中的发生率差异较大,病因复杂多样,且起病隐匿、进展迅速、病死率高。对肝移植围手术期脑卒中进行早期识别及诊断,及时进行有效治疗,对于改善患者预后具有重要意义。因此,本文就肝移植围手术期脑卒中的概念、发生情况、危险因素、诊断、治疗及预防进行综述,探讨肝移植围手术期脑卒中的研究进展,以期为肝移植围手术期脑卒中的诊治提供参考。Liver transplantation is one of the standard treatments for end-stage liver disease.With the development of surgical techniques and the optimization of perioperative management,the incidence of complications after liver transplantation has decreased,but perioperative neurological complications are still relatively common.The incidence of stroke varies greatly,with complex causes,as well as insidious onset,rapid progression and high fatality.Early identification and diagnosis of perioperative stroke after liver transplantation and timely effective treatment are of great significance for improving the prognosis of patients.Therefore,this article reviews the concept,occurrence,risk factors,diagnosis,treatment and prevention of perioperative stroke after liver transplantation,and explores the research progress of perioperative stroke after liver transplantation,in order to provide a reference for the diagnosis and treatment of perioperative stroke after liver transplantation.

关 键 词：肝移植 围手术期 脑卒中 脑梗死 脑出血 神经系统并发症 血栓 感染 

分 类 号：R617[医药卫生—外科学] R743[医药卫生—临床医学]