维生素A、D、E水平与妊娠期高血压疾病病情及预后的相关性  

Correlation of levels of vitamins A,D and E with the disease condition and prognosis of hypertensive disorder complicating pregnancy

作　　者：杨丽君[1] 杨志华 王利敏[1] Yang Lijun;Yang Zhihua;Wang Limin(Department of Obstetrics and Gynecology,Anyang Maternal and Child Health Care Hospital,Anyang 455000,China)

机构地区：[1]安阳市妇幼保健院妇产科,安阳455000

出　　处：《中国实用医刊》2024年第13期28-31,共4页Chinese Journal of Practical Medicine

摘　　要：目的:分析维生素A、D、E水平与妊娠期高血压疾病(HDCP)病情及预后的相关性。方法:回顾性抽取2018年6月至2019年2月安阳市妇幼保健院收治的HDCP孕妇198例为HDCP组,按照病情程度将其再分为妊娠期高血压组(51例)、子痫前期组(65例)、重度子痫前期组(82例),并以1∶1配比抽取同期健康体检孕妇198例为健康组。检测所有孕妇维生素A、D、E水平,比较检测结果,统计不同病情程度和不同预后HDCP患者维生素A、D、E水平,分析维生素A、D、E水平与HDCP病情及预后的相关性。结果:HDCP组维生素A、D、E水平低于健康组(P<0.05)。子痫前期组和重度子痫前期组维生素A、D、E水平低于妊娠期高血压组(P<0.05),重度子痫前期组维生素A、D、E水平低于子痫前期组(P<0.05)。预后不良HDCP孕妇维生素A、D、E水平低于预后良好HDCP孕妇(P<0.05)。Pearson结果显示,维生素A、D、E水平与HDCP病情及预后呈负相关(r=-0.48、-0.63、-0.57、-0.47、-0.62、-0.60,P均<0.05)。结论:HDCP孕妇维生素A、D、E水平明显降低,且维生素A、D、E水平与HDCP病情及预后存在相关性,病情越严重和预后越差其维生素A、D、E水平越低。Objective:To analyze the correlation of levels of vitamins A,D and E with the disease condition and prognosis of hypertensive disorder complicating pregnancy(HDCP).Methods:A total of 198 pregnant women with HDCP admitted to Anyang Maternal and Child Health Care Hospital from June 2018 to February 2019 were retrospectively selected as the HDCP group.According to the severity of the disease,they were further divided into the gestational hypertension group(51 cases),the preeclampsia group(65 cases)and the severe preeclampsia group(82 cases);and 198 pregnant women who underwent physical examination in the same period were selected as the healthy group at a ratio of 1∶1.The levels of vitamins A,D and E in all pregnant women were tested,and the test results were compared.The levels of vitamins A,D and E in HDCP patients with different degrees of disease severity and different prognoses were counted.The correlations of the levels of vitamins A,D and E with the disease condition and prognosis of HDCP were analyzed.Results:The levels of vitamins A,D and E in the HDCP group were lower than those in the healthy group(P<0.05).The levels of vitamins A,D and E in the preeclampsia group and the severe preeclampsia group were lower than those in the gestational hypertension group(P<0.05).The levels of vitamins A,D and E in the severe preeclampsia group were lower than those in the preeclampsia group(P<0.05).The levels of vitamins A,D and E in HDCP women with poor prognosis were lower than those in HDCP women with good prognosis(P<0.05).Results of Pearson analysis showed that the levels of vitamins A,D and E were negatively correlated with the disease condition and prognosis of HDCP(r=-0.48,-0.63,-0.57,-0.47,-0.62,-0.60;all P<0.05).Conclusions:The levels of vitamins A,D and E significantly decrease in pregnant women with HDCP,and they are correlated with the disease condition and prognosis of HDCP.Patients with worse severity of the disease and more poor prognosis have lower levels of vitamins A,D and E.

关 键 词：维生素A 维生素D 维生素E 妊娠期高血压疾病 预后 

分 类 号：R714.246[医药卫生—妇产科学]