基于Caprini风险评估模型的分级干预联合鼻饲温开水预防危重症患者下肢深静脉血栓的效果  

Effect of Graded Intervention Based on Caprini Risk Assessment Model Combined with Nasal Feeding with Warm Water on Prevention of Deep Vein Thrombosis of Lower Extremity in Critical Illness Patients

作　　者：李光磊 孙一珊 赵语嫣 王静[1] LI Guanglei;SUN Yishan;ZHAO Yuyan;WANG Jing(Department of Critical Care,Qilu Hospital of Shandong University,Jinan 250000,China;不详)

机构地区：[1]山东大学齐鲁医院重症医学科,山东济南250000 [2]山东大学齐鲁医院儿童血液科,山东济南250000

出　　处：《中国医学创新》2024年第23期82-86,共5页Medical Innovation of China

摘　　要：目的:分析基于Caprini风险评估模型的分级干预联合鼻饲温开水对危重症患者下肢深静脉血栓的预防价值。方法:根据随机数字表法将120例于2020年6月—2023年6月在山东大学齐鲁医院接受治疗的危重症患者分为两组。对照组(n=60)接受常规干预,观察组(n=60)接受基于Caprini风险评估模型的分级干预联合鼻饲温开水干预。对两组血液流变学、凝血指标、下肢深静脉血栓风险分级及下肢深静脉血栓发生率进行比较。结果:干预第7天,两组全血高切黏度、全血低切黏度、血小板聚集率和D-二聚体、凝血酶-抗凝血酶复合物均低于干预前,且观察组均低于对照组,两组凝血酶原时间均长于干预前,且观察组长于对照组,差异均有统计学意义(P<0.05);干预第7天,观察组下肢深静脉血栓风险分级优于对照组,下肢深静脉血栓发生率低于对照组,差异均有统计学意义(P<0.05)。结论:基于Caprini风险评估模型的分级干预与鼻饲温开水联合应用,可改善危重症患者的血液流变学和凝血功能,有效预防下肢深静脉血栓发生。Objective:To analyze the preventive value of graded intervention based on Caprini risk assessment model combined with nasal feeding with warm water on deep vein thrombosis of lower extremity in critical illness patients.Method:A total of 120 critical illness patients treated in Qilu Hospital of Shandong University from June 2020 to June 2023 were divided into two groups according to random number table method.The control group(n=60)received routine intervention,and the observation group(n=60)received graded intervention based on Caprini risk assessment model combined with nasal feeding with warm water intervention.The hemorheology,coagulation indexes,risk grade of deep vein thrombosis of lower extremity and the incidence of deep vein thrombosis of lower extremity were compared between the two groups.Result:On the 7th day of intervention,whole blood high shear viscosity,whole blood low shear viscosity,platelet aggregation rate,D-dimer and thrombine-antithrombin complex in both groups were lower than those before intervention,and those in observation group were lower than those in control group,prothrombin time in both groups were longer than those before intervention,and that in observation group was longer than that in control group,the differences were statistically significant(P<0.05).On the 7th day of intervention,the risk grade of deep vein thrombosis of lower extremity in observation group was better than that in control group,and the incidence of risk grade of deep vein thrombosis of lower extremity was lower than that in control group,the differences were statistically significant(P<0.05).Conclusion:The combination of graded intervention based on Caprini risk assessment model and nasal feeding with warm water can improve the hemorheology and coagulation function of critical illness patients,and effectively prevent the occurrence of grade of deep vein thrombosis of lower extremity.

关 键 词：Caprini风险评估模型 鼻饲温开水 下肢深静脉血栓 危重症 

分 类 号：R472[医药卫生—护理学]