归肾活血丸联合耳穴贴压对肾虚血瘀型月经过少的临床疗效研究  

Study on clinical efficacy of Guishen Huoxue Pill combined with ear acupoint pressing in treating oligomenorrhea of kidney deficiency and blood stasis type

作　　者：曾丽[1] 陈莉[1] 俎丽[1] ZENG Li;CHEN Li;ZU Li(The Seventh Clinical Medical College of Guangzhou University of Traditional Chinese Medicine,Shenzhen 518000,China)

机构地区：[1]广州中医药大学第七临床医学院,518000

出　　处：《中国实用医药》2024年第16期150-153,共4页China Practical Medicine

摘　　要：目的探讨归肾活血丸联合耳穴贴压对肾虚血瘀型月经过少的临床疗效。方法106例肾虚血瘀型月经过少患者,采用随机数字表法分为对照组及观察组,每组53例。对照组采用西医治疗,观察组采用归肾活血丸联合耳穴贴压治疗。对比两组患者治疗后临床疗效,治疗前后的月经量评分、子宫内膜厚度、内分泌激素[血清卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E_(2))、抗缪勒式管激素(AMH)]水平。结果与对照组75.47%对比,观察组患者治疗总有效率96.23%显著更高(P<0.05)。治疗后,两组患者月经量评分低于治疗前、子宫内膜厚度大于治疗前,且观察组患者月经量评分(2.56±0.39)分低于对照组的(3.12±0.57)分、子宫内膜厚度(10.12±1.05)mm大于对照组的(9.05±1.24)mm(P<0.05)。治疗后,两组患者FSH、LH、E_(2)均显著低于治疗前,AMH高于治疗前,且观察组患者FSH(7.65±1.06)U/L、LH(5.87±1.97)U/L、E_(2)(58.14±2.16)pmol/L均显著低于对照组的(10.83±0.98)U/L、(6.76±1.02)U/L、(69.71±2.05)pmol/L,AMH(2.20±0.71)ng/ml高于对照组的(1.76±0.63)ng/ml(P<0.05)。结论归肾活血丸联合耳穴贴压对肾虚血瘀型月经过少疗效确切,可改善月经量,对临床相关症状有明显的缓解作用,促进激素内分泌水平稳定,使子宫内膜的厚度有所增厚,疗效满意,值得临床推广运用。Objective To explore the clinical efficacy of Guishen Huoxue Pill combined with ear acupoint pressing in treating oligomenorrhea of kidney deficiency and blood stasis type.Methods 106 patients with oligomenorrhea of kidney deficiency and blood stasis type were divided into a control group and an observation group using a random number table method,with 53 cases in each group.The control group was treated with Western medicine,while the observation group was treated with Guishen Huoxue Pill combined with ear acupoint pressing.Patients in both groups were compared in terms of clinical efficacy after treatment,menstrual volume score,endometrial thickness,and levels of endocrine hormones[serum follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E_(2))and anti-Mullerian hormone(AMH)]before and after treatment.Results Compared with 75.47%in the control group,the total effective rate in the observation group was higher at 96.23%(P<0.05).After treatment,the menstrual volume score in both groups was lower than that before treatment,and the endometrial thickness was higher than that before treatment;the menstrual volume score of(2.56±0.39)points in the observation group was lower than(3.12±0.57)points in the control group,and the endometrial thickness of(10.12±1.05)mm was higher than(9.05±1.24)mm in the control group(P<0.05).After treatment,FSH,LH and E_(2)in both groups were significantly lower than those before treatment,and AMH was higher than that before treatment;the observation group had FSH of(7.65±1.06)U/L,LH of(5.87±1.97)U/L and E_(2)of(58.14±2.16)pmol/L,which were significantly lower than(10.83±0.98)U/L,(6.76±1.02)U/L and(69.71±2.05)pmol/L in the control group;the AMH of(2.20±0.71)ng/ml in the observation group was higher than(1.76±0.63)ng/m in the control groupl(P<0.05).Conclusion Guishen Huoxue Pill combined with ear acupoint pressing has definite curative effect on kidney deficiency and blood stasis type of oligomenorrhea and has obvious relieving effect on clinical symptoms,which c

关 键 词：月经过少 肾虚血瘀型 归肾活血丸 耳穴贴压 激素内分泌水平 临床疗效 

分 类 号：R271.111[医药卫生—中医妇科学]