血小板计数、D-二聚体与凝血四项对颅脑外伤患者预后的预测价值  

Prognostic value of platelet count,D-dimer and coagulation in patients with craniocerebral trauma

作　　者：陈文青 邱素娟[2] 蔡巧萍 Chen Wenqing;Qiu Sujuan;Cai Qiaoping(Department of Clinical Laboratory,Xinglin Hospital,the First Affiliated Hospital of Xiamen University,Xiamen 361022,China;Department of Clinical Laboratory,The First Affiliated Hospital of Xiamen University,Xiamen 361000,China)

机构地区：[1]厦门大学附属第一医院杏林院区检验科,福建厦门361022 [2]厦门大学附属第一医院检验科,福建厦门361000

出　　处：《西藏医药》2024年第4期22-24,共3页Tibetan Medicine

摘　　要：目的目的探究血小板计数、D-二聚体与凝血四项对颅脑外伤患者预后的预测价值。方法方法收集我院2021年4月~2023年4月收治的颅脑外伤患者89例。根据患者预后进行分组,分为预后良好为良好组(68例)和预后不良为不良组(21例)。比较患者一般资料、血小板计数、D-二聚体、PT、APTT、TT、FIB;受试者操作特征曲线(ROC)下面积(AUC)分析血小板计数、D-二聚体、PT、APTT、TT、FIB对颅脑外伤患者预后的预测价值。结果结果两组性别、年龄、体质量指数、吸烟、高血压、糖尿病比较差异无统计学意义(P>0.05)。不良组血小板计数、FIB低于良好组,D-二聚体、PT、APTT、TT高于良好组,(P<0.05)。血小板计数、D-二聚体与凝血四项对颅脑外伤患者预后的预测价值良好,灵敏度、特异度相对单一指标较好,AUC最大,为0.968,灵敏度为0.857,特异度为0.985。血小板计数、D-二聚体与凝血四项的预测阈值分别为189.080×10^(9)/L、0.795mg/L、13.610s、31.475s、15.840s、2.980g/L。结论结论血小板计数、D-二聚体与凝血四项对颅脑外伤患者预后的预测价值良好,可作为临床上颅脑外伤患者预后的评估因子。Objective To investigate the prognostic value of platelet count,D-dimer and coagulation in patients with craniocere-bral trauma.Methods The clinical data of 89 patients with craniocerebral trauma admitted to our hospital from April 2021 to April 2023 were collected.According to the prognosis,the patients were divided into good group(68 cases)and poor group(21 cases).General data,platelet count,D-dimer,PT,APTT,TT,FIB were compared.The predictive value of platelet count,D-dimer,PT,APTT,TT and FIB in patients with craniocerebral trauma was analyzed by area under receiver operating characteristic curve(ROC)(AUC).Results There were no significant differences in gender,age,body mass index,smoking,hypertension and diabetes between the two groups(P>0.05).The platelet count and FIB of the poor group were lower than those of the good group,and the D-dimer,PT,APTT and TT of the poor group were higher than those of the good group,the differences were significant(P<0.05).Platelet count,D-dimer and coagulation had good predictive value for the prognosis of patients with cranial trauma,and the sensitivity and specificity were better than that of a single index.AUC was 0.968,sensitivity was 0.857,and specificity was 0.985.The predicted thresholds for platelet count,D-dimer and coagulation were 189.080×10^(9)/L,0.795mg/L,13.610s,31.475s,15.840s and 2.980g/L,re-spectively.Conclusion Platelet count,D-dimer and coagulation have good prognostic value for patients with craniocerebral trauma,and can be used as prognostic factors for patients with craniocerebral trauma.

关 键 词：血小板计数 D-二聚体 凝血四项 颅脑外伤 

分 类 号：R651.15[医药卫生—外科学] R446.11[医药卫生—临床医学]