The Astronaut Center of China 90-d Head-Down Bed Rest:Overview,Countermeasures,and Effects  

作　　者：Linjie Wang Zhili Li Shujuan Liu Jianfeng Zhang Xiaoqian Dai Zhongquan Dai Chong Xu Yanlei Wang Peng Zang Zhifeng Guo Lina Qu Yinghui Li 

机构地区：[1]State Key Laboratory of Space Medicine Fundamentals and Application,China

出　　处：《Space(Science & Technology)》2023年第1期176-192,共17页空间科学与技术（英文）

基　　金：supported by the China Manned Space Flight Engineering Advance Research Program(grant number HY-5);the Foundation of State Key Laboratory of Space Medicine Fundamentals and Application(grant number SMFA18A01);a Space Medical Experiment grant(grant number HYZHXM01001).

摘　　要：Countermeasures in weightlessness are a predominant technique for long-term residency in space.Head-down bed rest(HDBR)has long been used to simulate the physiological effects of spaceflight and test the efficacy of countermeasures.In 2019,the Astronaut Center of China(ACC)has held a 90-d HDBR on the effects of exercises’intervention.Thirty-six subjects were recruited and randomized into 5 intervention groups:(a)control,(b)aerobic exercises,(c)resistance exercises,(d)concurrent aerobic and lower load resistance exercises,and(e)concurrent aerobic and high-load resistance exercises.Moreover,exercise interventions were performed in supine or 6°head-down tilt.They were provided with plain medical,psychological,and nutritional supports during the experiment.In addition,cardiovascular and pulmonary functions,muscle strength,bone density,and neuro-immune-endocrine functions were assessed over time.Subjects were monitored by clinical evaluations,psychological assessments,and nutritional status evaluations.All subjects spent 138 d in the bed rest study laboratory and received 2 follow-up tests per 3 months in the home recovery period.It was found that exercises in the 4 groups were effective interventions for aerobic capacity compared with control.The resistance exercises or concurrent aerobic and high-load resistance exercises improved isometric maximal voluntary contraction.However,the protection against bone loss still needs further exploration.Appropriate psychosocial and nutrition support techniques are worth to be reinforced.

关 键 词：HAS PLAIN CONCURRENT 

分 类 号：V527[航空宇航科学与技术—人机与环境工程]