The impact of COVID-19 on clinical outcomes of burn patients  

作　　者：Elliot T.Walters Alen Palackic Camila Franco-Mesa Nikhil R.Shah Michael J.Erickson Steven E.Wolf 

机构地区：[1]Department of Surgery,University of Texas Medical Branch,301 University,Galveston,TX,USA [2]Division of Plastic,Aesthetic and Reconstructive Surgery,Department of Surgery,Medical University of Graz,Graz,Austria

出　　处：《Burns & Trauma》2023年第1期792-799,共8页烧伤与创伤（英文）

基　　金：supported by the Institute for Translational Sciences at the University of Texas Medical Branch,supported in part by a Clinical and Translational Science Award(UL1 TR001439)。

摘　　要：Background:Multiple studies have shown the SARS-CoV-2 virus(COVID-19)to be associated with deleterious outcomes in a wide range of patients.The impact of COVID-19 has not been well investigated among burned patients.We suspect that patients will have worsened respiratory and thrombotic complications,ultimately leading to increased mortality.The objective of this study is to determine the impact a concurrent infection of COVID-19 has on clinical outcomes after a burn injury.Methods:This is a retrospective,propensity matched,cohort study.We examined a de-identified database of electronic medical records of over 75 million patients across 75 health care associations in the United States for patients treated for thermal burns from 1 January 2020,to 31 July 2021,and those who also were diagnosed with COVID-19 infection within one day before or after injury based on International Classification of Disease,tenth revision(ICD-10)codes.Study participants included adults who were treated for a burn injury during the study period.Results:We included 736 patients with burn injury and concomitant COVID-19 infection matched to 736 patients with burn injury and no concurrent COVID-19 infection(total 1472 patients,mean age 36.3±24.3).We found no significant increase in mortality observed for patients with concurrent COVID-19(OR 1.203,95%CI 0.517-2.803;p=0.6675).We did observe significant increase in infections(OR 3.537,95%CI 2.798-4.471;p=0.0001),thrombotic complications(OR 2.342,95%CI 1.351-4.058;p=0.0018),as was the incidence of hypertrophic scarring(OR 3.368,95%CI 2.326-4.877;p=0.0001).Conclusions:We observed that concurrent COVID-19 infection was associated with an increase in infections,thrombosis and hypertrophic scarring but no increase in mortality in our cohort of burn patients.

关 键 词：COVID-19 INFECTION MORTALITY BURN THROMBOSIS SCARRING 

分 类 号：R563.1[医药卫生—呼吸系统]