术前LCR联合HALP评分对持续性房颤患者射频消融术预后的评估效能  

Efficacy of preoperative lymphocyte/C⁃reactive protein ratio combined with HALP score in the prognosis of cases with persistent atrial fibrillation undergoing radiofrequency ablation

作　　者：张颖 南景龙 吴广 任海荣 ZHANG Ying;NAN Jinglong;WU Guang;REN Hairong(Department of Cardiology,Inner Mongolia Autonomous Region People's Hospital,Inner Mongolia Autono-mous Region,China,010017)

机构地区：[1]内蒙古自治区人民医院心内科,内蒙古自治区呼和浩特010017

出　　处：《分子诊断与治疗杂志》2024年第8期1480-1483,1492,共5页Journal of Molecular Diagnostics and Therapy

基　　金：内蒙古自治区卫生健康科技计划项目(202301027)。

摘　　要：目的探讨术前淋巴细胞/C反应蛋白比值(LCR)联合血红蛋白⁃白蛋白⁃淋巴细胞⁃血小板(HALP)评分对持续性心房颤动(房颤)患者射频消融术预后的评估效能。方法选取2020年9月至2023年8月于内蒙古自治区人民医院行射频消融术的102例持续性房颤患者,根据术后复发情况分为复发组(24例)和非复发组(78例)。比较两组术前LCR、HALP评分;采用受试者工作特性曲线(ROC)评估术前LCR、HALP评分对持续性房颤患者射频消融术后复发的预测价值;分析持续性房颤患者射频消融术后复发的单因素、多因素。结果复发组术前LCR、HALP评分高于非复发组,差异有统计学意义(P<0.05)。术前LCR、HALP评分及两者联合预测持续性房颤患者射频消融术后复发的曲线下面积(AUC)分别为0.837、0.759、0.904。复发组女性占比、高血压史占比高于非复发组,BMI、病程、LAD大于非复发组,差异有统计学意义(P<0.05)。二分类Logistic逐步回归分析显示,病程长、有高血压史、LAD增加、术前LCR水平低、术前HALP评分低是持续性房颤患者术后复发的独立危险因素(P<0.05)。结论术前LCR水平、HALP评分低与持续性房颤患者术后复发密切相关,两者可作为预测术后复发的重要指标。Objective To evaluate the efficacy of preoperative lymphocyte/C⁃reactive protein ratio(LCR)combined with hemoglobin⁃albumin⁃lymphocyte⁃platelet(HALP)score in the prognosis of cases with persistent atrial fibrillation(AF)after radiofrequency ablation.Methods A total of 102 cases with persistent atrial fibrillation who underwent radiofrequency ablation at Inner Mongolia Autonomous Region People's Hospi⁃tal from September 2020 to August 2023 were selected and divided into a recurrence group(24 cases)and a non recurrence group(78 cases)based on postoperative recurrence.Measurement data were described Using(x±s)and analyze with a t⁃test,while count data were described in n(%),and analyzed using χ^(2) inspection.Receiver operating characteristic(ROC)curve was used to evaluate the predictive value of preoperative LCR and HALP scores in cases with persistent atrial fibrillation after radiofrequency ablation.Factors affecting recurrence in cases with persistent atrial fibrillation after radiofrequency ablation were explored through binary logistic stepwise re⁃gression analysis.Results The preoperative LCR and HALP scores of the recurrent group were higher than those of the non recurrent group,and the difference was statistically significant(P<0.05).The area under the curve(AUC)of preoperative LCR,HALP score,and their combined prediction for recurrence after radiofre⁃quency ablation in patients with persistent atrial fibrillation were 0.837,0.759,and 0.904,respectively.The pro⁃portion of women in the recurrent group and the history of hypertension were higher than those in the non recur⁃rent group,and the BMI,disease duration,and LAD were higher than those in the non recurrent group,with sta⁃tistically significant differences(P<0.05).Binary logistic stepwise regression analysis showed that long disease course,history of hypertension,increased LAD,low preoperative LCR levels,and low preoperative HALP score were independent risk factors for postoperative recurrence in patients with persistent atrial f

关 键 词：持续性房颤 射频消融术 淋巴细胞/C反应蛋白比值 HALP评分 

分 类 号：R541.75[医药卫生—心血管疾病]