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作 者:Weiyi Liu Huanyu Cheng Xiufeng Wang
机构地区:[1]School of Materials Science and Engineering,Xiangtan University,Xiangtan,Hunan 411105,China [2]Department of Engineering Science and Mechanics,The Pennsylvania State University,University Park,PA 16802,USA
出 处:《npj Flexible Electronics》2023年第1期100-108,共9页npj-柔性电子(英文)
基 金:supported by the National Natural Science Foundation of China(12172319 and 11872326);Natural Science Foundation of Hunan Province(2021JJ30648 and 2021JJ30641);Scientific Research Fund(22A0130)of Hunan Provincial Education Department,Furong Scholars Programme of Hunan Province,“Chunhui Program”Cooperative Research Fund(HZKY20220357);the Ministry of Education,and Postgraduate Scientific Research Innovation Project of Hunan Province(CX20230658);H.C.also acknowledges the support from the National Institutes of Health(Award Nos.R21EB030140,R21OH012220,and R61HL154215);the National Science Foundation(NSF)(Grant Nos.ECCS-2222654 and 1933072),and Penn State University.
摘 要:As sweat biomarker levels are continuously changing over metabolism and daily activities,pathological and physiological processes can be dynamically analyzed by wearable devices.The colorimetric skin-interfaced microfluidic devices that do not have external circuit modules exhibit enhanced deformability with a small footprint.However,it is difficult to achieve sampling over time and self-feedback for closed-loop systems.This review summarizes recent advances in microfluidic valves for biofluid management and chrono-sampling,as well as active triggers in microfluidics self-feedback.After enumerating the current limitations in temporal resolution and reliability,we further point out a few potential feasible strategies for future developments.
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