Spider-inspired tunable mechanosensor for biomedical applications  

作　　者：Taewi Kim Insic Hong Yeonwook Roh Dongjin Kim Sungwook Kim Sunghoon Im Changhwan Kim Kiwon Jang Seongyeon Kim Minho Kim Jieun Park Dohyeon Gong Kihyeon Ahn Jingoo Lee Gunhee Lee Hak-Seung Lee Jeehoon Kang Ji Man Hong Seungchul Lee Sungchul Seo Bon-Kwon Koo Je-sung Koh Seungyong Han Daeshik Kang 

机构地区：[1]Department of Mechanical Engineering,Ajou University,Suwon,Korea [2]Department of Mechanical Engineering,Pohang University of Science and Technology,Pohang,Korea [3]Department of Sustainable Environment Research,Korea Institute of Machinery&Materials,Daejeon,Korea [4]Department of Internal Medicine and Cardiovascular Center,Seoul National University Hospital,Seoul,Korea [5]Department of Neurology and Neurosurgery,Ajou University School of Medicine,Suwon,Korea [6]Department of Nano-chemical,Biological and Environmental Engineering,Seokyeong University,Seoul,Korea [7]Institute on Aging,Seoul National University,Seoul,Korea

出　　处：《npj Flexible Electronics》2023年第1期444-452,共9页npj-柔性电子（英文）

基　　金：supported by funding from NRF of Korea(grant no.2019R1H1A1080221,2019R1F1A1063066,2019R1C1C1007629,2021R1A6A3A01087289,2021R1A6A3A13045869,2022R1A2C2093100,2022R1A6A3A13071489);supported by Korea Environment Industry&Technology Institute(KEITI)through Digital Infrastructure Building Project for Monitoring,Surveying,and Evaluating the Environmental Health Program,funded by Korea Ministry of Environment(MOE)(2021003330009);supported by a grant of the Basic Research Program funded by the Korea Institute of Machinery and Materials(grant number:NK231A).

摘　　要：The recent advances of wearable sensors are remarkable but there are still limitations that they need to be refabricated to tune the sensor for target signal.However,biological sensory systems have the inherent potential to adjust their sensitivity according to the external environment,allowing for a broad and enhanced detection.Here,we developed a Tunable,Ultrasensitive,Nature-inspired,Epidermal Sensor(TUNES)that the strain sensitivity was dramatically increased(GF~30k)and the pressure sensitivity could be tuned(10–254 kPa^(−1))by preset membrane tension.The sensor adjusts the sensitivity to the pressure regime by preset tension,so it can measure a wide range(0.05 Pa–25 kPa)with the best performance:from very small signals such as minute pulse to relatively large signals such as muscle contraction and respiration.We verified its capabilities as a wearable health monitoring system by clinical trial comparing with pressure wire which is considered the current gold standard of blood pressure(r=0.96)and home health care system by binary classification of Old’s/Young’s pulse waves via machine learning(accuracy 95%).

关 键 词：SENSOR ADJUST SPIDER 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]