双C干预方案对2型糖尿病合并卵巢癌患者化疗期间血糖波动变化、血糖达标时间及胰岛素用量的影响  

Effects of Double C Intervention Regimen on Blood Glucose Fluctuation,Blood Glucose Compliance Time and Insulin Dosage during Chemotherapy in Patients with Type 2 Diabetes Mellitus Complicated with Ovarian Cancer

作　　者：车祺蓉 黄蓉蓉 张雪萍 CHE Qirong;HUANG Rongrong;ZHANG Xueping(Department of Oncology,Joint Logistics Support Force 910 Hospital,Quanzhou 362000,Fujian,China)

机构地区：[1]联勤保障部队910医院肿瘤内科,福建泉州362000

出　　处：《糖尿病新世界》2024年第12期101-104,共4页Diabetes New World

摘　　要：目的分析化疗治疗期间2型糖尿病合并卵巢癌患者接受双C干预方案对血糖波动变化、血糖达标时间及胰岛素用量影响。方法选取2022年9月—2023年9月联勤保障部队910医院肿瘤内科收治的90例接受化疗治疗的2型糖尿病合并卵巢癌患者为研究对象,按照血糖控制方式的不同分为对照组及观察组,各45例。其中对照组采取常规血糖干预,观察组采取双C干预方案。比较两组血糖波动变化(平均血糖波动幅度和日间血糖平均绝对差)、血糖达标时间及胰岛素用量。结果干预后,两组血糖波动变化、血糖达标时间及胰岛素用量相比于干预前均得到显著改善,且观察组平均血糖波动幅度、日间血糖平均绝对差和胰岛素用量均低于对照组,血糖达标时间高于对照组,差异有统计学意义(P均<0.05)。结论在接受化疗治疗期间,2型糖尿病合并卵巢癌患者采取常规血糖干预手段具有一定效果,但存在较大提升空间。相比于常规用药控制及营养支持等途径,双C干预方案可显著改善患者血糖波动变化幅度,提升血糖日达标时间并降低胰岛素用量,帮助患者更为安全高效地接受临床治疗。Objective To analyze the effects of double C intervention on blood glucose fluctuation,blood glucose com-pliance time and insulin dosage in patients with type 2 diabetes mellitus complicated with ovarian cancer during che-motherapy.Methods From September 2022 to September 2023,90 patients with type 2 diabetes mellitus complicated with ovarian cancer who received chemotherapy in the Department of Oncology of Joint Logistics Support Force 910 Hospital were selected as the research objects.According to the different blood glucose control methods,they were di-vided into control group and observation group,45 cases in each group.The control group received routine blood glu-cose intervention,and the observation group received double C intervention program.The changes of blood glucose fluctuation(awerage blood glucose fluctuation range and absolute difference of daytime blood glucose average),blood glucose compliance time and insulin dosage were compared between the two groups.Results After intervention,the changes of blood glucose fluctuation,blood glucose compliance time and insulin dosage in the two groups were signifi-cantly improved compared with those before intervention,the average blood glucose fluctuation range,the absolute dif-ference of daytime blood glucose average and insulin dosage in the observation group were lower than those in the con-trol group,and blood glucose compliance time was higher than that in the control group,the differences were statisti-cally significant(all P<0.05).Conclusion During the period of chemotherapy,patients with type 2 diabetes mellitus complicated with ovarian cancer have a certain effect on routine blood glucose intervention,but there is a large room for improvement.Compared with routine medication control and nutritional support,the double C intervention program can significantly improve the fluctuation range of blood glucose,improve the daily blood glucose compliance time and reduce the insulin dosage,so as to help patients receive clinical treatment more safely and efficie

关 键 词：化疗 2型糖尿病 卵巢癌 双C 血糖 胰岛素 

分 类 号：R587.2[医药卫生—内分泌]