基于DNA纳米技术的晶体材料构建  

Crystal Material Construction Based on DNA Nanotechnology

作　　者：李培鑫 彭牧石 闫学慧 余一帆 田野 Peixin Li;Mushi Peng;Xuehui Yan;Yifan Yu;Ye Tian(College of Engineering and Applied Sciences,State Key Laboratory of Analytical Chemistry for Life Science,Chemistry and Biomedicine Innovation Center,Nanjing University,Nanjing 210023,China)

机构地区：[1]南京大学现代工程与应用科学学院生命分析化学国家重点实验室化学与生物医药创新研究院,南京210023

出　　处：《化学进展》2024年第7期949-960,共12页Progress in Chemistry

基　　金：江苏省自然科学基金项目(No.BK20220124);国家自然科学基金项目(No.22372077,92356304);南京大学生命分析化学国家重点实验室自主研究项目(No.5431ZZXM2301)资助。

摘　　要：纳米颗粒晶体在电学、光学、磁学等方面具有独特的性质与优越的性能,人工构建纳米颗粒晶体对于材料科学的功能突破和性能发展具有重要意义。DNA由于其具有碱基互补配对的特性,可以用于构建各种纳米级结构、组装晶体并调控结构与组成,从而实现材料特定性能的定制。目前,DNA纳米技术构建的纳米颗粒晶体材料已经在催化剂、光学器件、半导体材料等方面实现了应用,表明其构建三维晶体作为普适的周期性分子支架的基本目标逐步实现。在这篇综述里,我们系统性地阐述了DNA瓦片、可编程原子等价物、DNA折纸三种重要DNA纳米晶体构建技术的发展历程与最近的研究进展,并对利用DNA纳米技术构建晶体材料的未来发展方向进行了讨论。Nanocrystal materials have exhibited unique and superior properties in the fields of electronics,optics,and magnetism.The fabrication of nanocrystal materials holds significant importance in the material science for achieving breakthroughs and further developments in their performance.DNA,known for its complementary base pairing characteristics,offers the potential to construct diverse nanostructures and crystals of which the structures and composition can be precisely controlled,thereby enabling the tailored material properties.Currently,the nanocrystal materials fabricated through DNA nanotechnology has been applied in various fields,including catalysts,optical devices,and semiconductor materials.These advancements signify a progressive realization of the fundamental objective for constructing three-dimensional crystals as versatile,periodic molecular frameworks.In this review,we provide a systematic elucidation of the development and recent advancements in the research pertaining to three pivotal techniques employed in the construction of DNA nanocrystals.These techniques include DNA tiles,programmable atomic equivalents,and DNA origami.Moreover,we briefly deliberate on the future direction of utilizing DNA nanotechnology in the construction of nanocrystal materials.

关 键 词：DNA纳米技术 可编程原子等价物 DNA折纸 自组装 

分 类 号：Q523[生物学—生物化学] TB383[一般工业技术—材料科学与工程] O7[理学—晶体学]