北京石景山区40岁以上PRISm和COPD患者的肺功能水平与吸烟情况相关性分析  

Correlation between lung function and smoking status in patients with preserved-ratio impaired spirometry and chronic obstructive pulmonary disease over 40 years of age in Shijingshan district of Beijing

作　　者：张克 张二明[1] 闫维 马石头 安欣华 包曹歆 向平超[1] Ke Zhang;Erming Zhang;Wei Yan;Shitou Ma;Xinhua An;Caoxin Bao;Pingchao Xiang(Department of Pulmonary and Critical Care Medicine,Peking University Shougang Hospital,Beijing 100144,China;Shijingshan District Center for Disease Control and Prevention,Beijing 100144,China)

机构地区：[1]北京大学首钢医院呼吸与危重症医学科,北京100144 [2]石景山区疾病预防控制中心,北京100144

出　　处：《中华临床医师杂志（电子版）》2024年第2期122-127,共6页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨北京市石景山区40岁以上比率保留的肺功能减损(PRISm)患者与慢性阻塞性肺疾病(COPD)患者的肺功能水平与吸烟情况的关系。方法数据源于2019年6月~12月北京市石景山辖区内40岁以上人群的肺功能筛查结果,根据肺功能测定判定为PRISm患者477例,COPD患者416例,根据当前吸烟状况分为不吸烟组,已戒烟组和仍在吸烟组,并对6组患者的肺功能水平进行比较。结果416例COPD患者中男性患者占比62.5%,女性患者37.5%,PRISm患者中男性占56.4%,女性43.6%。肺功能相关指标FEV1/FVC,FEV1%pred.的改变与吸烟现状密切相关,但与被动吸烟状况无明显统计差异。两组患者人群中,根据当前吸烟现况可见,已戒烟患者人数明显多于仍在吸烟组。通过相关性分析发现,COPD患者的吸烟年限和吸烟量与肺功能的下降水平密切相关(P<0.05),同时FEV1/FVC也与戒烟年数呈负相关性。结论肺功能水平改变与吸烟情况密切相关。早期采取肺功能检查对人群进行筛查并根据其吸烟情况进行早期干预和随访,有利于降低慢阻肺相关的发病率。Objective To investigate the relationship between pulmonary function and smoking status in patients with preserved-ratio impaired spirometry(PRISm)and chronic obstructive pulmonary disease(COPD)over 40 years of age in Shijingshan district of Beijing.Methods Data were obtained from people over 40 years old in Shijingshan district of Beijing who underwent lung function screening from June to December 2019.According to lung function measurements,477 patients were diagnosed with PRISm and 416 had COPD.They were divided into a non-smoking group,a past smoking group,and a current smoking group according to current smoking status,and the lung function was compared among the three groups.Results Among the 416 COPD patients,62.5%were male and 37.5%were female,while 56.4%of PRISm patients were male and 43.6%were female.Changes in the lung function-related indexes FEV1/FVC and FEV1%pred were closely related to current smoking status,but had no statistically significant association with passive smoking status.The number of patients who had smoking cessation was significantly higher than that of those who were still smoking according to their current smoking status.Correlation analysis showed that the number of years of smoking and the amount of cigarettes smoked in patients with COPD were strongly correlated with lung function decline(P<0.05),and FEV1/FVC was negatively correlated with the number of years of smoking cessation.Conclusion Smoking status is closely related to the change in lung function in Chinese people with COPD.Early screening of the population by pulmonary function testing and early intervention and follow-up according to their smoking status are beneficial to reduce the incidence of COPD.

关 键 词：比率保留的肺功能减损 慢性阻塞性肺疾病 肺功能 吸烟 

分 类 号：R563[医药卫生—呼吸系统]