Rapid fabrication of reconfigurable helical microswimmers with environmentally adaptive locomotion  

作　　者：Rui Li Yuan Tao Jiawen Li Dongdong Jin Chen Xin Shengyun Ji Chaowei Wang Yachao Zhang Yanlei Hu Dong Wu Li Zhang Jiaru Chu 

机构地区：[1]CAS Key Laboratory of Mechanical Behavior and Design of Materials,Department of Precision Machinery and Precision Instrumentation,University of Science and Technology of China,Hefei 230026,China [2]Department of Mechanical and Automation Engineering,The Chinese University of Hong Kong,Hong Kong 999077,China

出　　处：《Light(Advanced Manufacturing)》2023年第4期42-54,共13页光（先进制造）（英文）

基　　金：supported by the Major Scientific and Technological Projects in Anhui Province(202103a05020005);National Natural Science Foundation of China(Nos.52075516,61927814,and 52122511);National Key Research and Development Program of China(No.2021YFF0502700);Major Scientific and Technological Projects in Anhui Province(201903a05020005);China Postdoctoral Science Foundation(2023M733381 and 2021M703120);USTC Research Funds of the Double First-Class Initiative(YD2340002009);the Joint Fund for New Medicine of USTC(YD2090002016);the CAS Project for Young Scientists in Basic Research(No.YSBR-049);L.Z.would like to thank the Hong Kong Research Grant Council for support with Project No.JLFS/E-402/18;the Croucher Foundation Grant with Ref.No.CAS20403.

摘　　要：Artificial helical microswimmers with shape-morphing capacities and adaptive locomotion have great potential for precision medicine and noninvasive surgery.However,current reconfigurable helical microswimmers are hampered by their low-throughput fabrication and limited adaptive locomotion.Here,a rotary holographic processing strategy(a helical femtosecond laser beam)is proposed to produce stimuli-responsive helical microswimmers(<100μm)rapidly(<1 s).This method allows for the easy one-step fabrication of various microswimmers with controllable sizes and diverse bioinspired morphologies,including spirulina-,Escherichia-,sperm-,and Trypanosoma-like shapes.Owing to their shape-morphing capability,the helical microswimmers undergo a dynamic transition between tumbling and corkscrewing motions under a constant rotating magnetic field.By exploiting adaptive locomotion,helical microswimmers can navigate complex terrain and achieve targeted drug delivery.Hence,these microswimmers hold considerable promise for diverse precision treatments and biomedical applications.

关 键 词：Femtosecond laser beam Rotary holographic processing Helical microswimmer Shape morphing Adaptive locomotion 

分 类 号：O43[机械工程—光学工程]