氨基甘油Gemini表面活性剂的合成与性质研究  

Synthesis and properties of amino⁃glycerol Gemini surfactant

作　　者：贾晨悦 施亮亮 唐红 冯江涛 贺军波 张维农[1,2,3] JIA Chen-yue;SHI Liang-liang;TANG Hong;FENG Jiang-tao;HE Jun-bo;ZHANG Wei-nong(Key Laboratory for Deep Processing of Major Grain and Oil of Ministry of Education,School of Food Science and Engineering,Wuhan Polytechnic University,Wuhan 430023,China;Hubei Key Laboratory for Processing and Transformation of Agricultural Products,Wuhan Polytechnic University,Wuhan 430023,China;Hubei Engineering Research Center of Lipid-based Fine Chemical Industry,Wuhan 430023,China)

机构地区：[1]武汉轻工大学食品科学与工程学院,大宗粮油精深加工教育部重点实验室,湖北武汉430023 [2]武汉轻工大学,农产品加工与转化湖北省重点实验室,湖北武汉430023 [3]湖北省油脂精细化工工程技术研究中心,湖北武汉430023

出　　处：《现代化工》2024年第S01期111-117,共7页Modern Chemical Industry

基　　金：国家自然科学基金青年基金(21807084)。

摘　　要：以脂肪胺、缩水甘油及1,3-二氯-2-丙醇为原料,合成了一系列甘油胺为头基、羟基丙烷为连接基的非离子型Gemini表面活性剂。通过核磁共振(1HNMR、13CNMR)、高分辨质谱(HRMS)、傅里叶红外光谱(FT-IR)对产物的结构进行表征,并研究了它们的表面活性、润湿性、乳化性、起泡性和抑菌活性。结果表明,8-3(OH)-8在2.02 mmol/L时有较好的降低表面张力的效果,12-3(OH)-12具有最好的发泡性以及乳化性;8-3(OH)-8和12-3(OH)-12在水溶液中均呈稳定的纳米分散体系;8-3(OH)-8对金黄色葡萄球菌和大肠杆菌都有最好的抑菌效果,在40μg/mL时抑菌率达90%以上。羟基丙烷为连接基的脂肪氨基甘油Gemini表面活性剂具有良好的应用前景。A series of nonionic Gemini surfactants with glycerol amine as the head group and hydroxypropane as the spacer are synthesized from aliphatic amine,glycidol,and 1,3⁃dichloro⁃2⁃propanol.The structure of the products is characterized by means of nuclear magnetic resonance(1HNMR and 13CNMR),high⁃resolution mass spectrometry(HRMS),and Fourier⁃transform infrared spectroscopy(FT⁃IR).Furthermore,their surface activity,wettability,emulsifying ability,foaming properties,and antibacterial activity are studied too.Study results show that 8⁃3(OH)⁃8 product has a good effect on reducing surface tension at 2.02 mmol·L^(-1),and 12⁃3(OH)⁃12 product shows the best foaming and emulsifying properties.Both 8⁃3(OH)⁃8 and 12⁃3(OH)⁃12 products present stable nano⁃dispersion system in aqueous solution.The 8⁃3(OH)⁃8 product has the best antibacterial effect against Staphylococcus aureus and Escherichia coli,with an inhibition rate of over 90%at 40μg·mL^(-1).In a sum,the aliphatic amino⁃glycerol Gemini surfactants with hydroxypropane as the spacer have good application prospects.

关 键 词：GEMINI表面活性剂 羟基丙烷 合成 表面活性 

分 类 号：TH3[机械工程—机械制造及自动化]