保元逐瘀护心汤、雷火灸联合西药治疗冠心病心力衰竭的临床效果  

Clinical Effect of Baoyuan Zhuyu Huxin Decoction and Thunder Fire Moxibustion Combined with Western Medicine in the Treatment of Coronary Heart Disease Heart Failure

作　　者：吕永飞[1] 陈爱莲[1] 孙玮琦 王利民[1] 张庆冉 LYU Yongfei;CHEN Ailian;SUN Weiqi;WANG Limin;ZHANG Qingran(Department of Cardiology and Geriatrics,Puyang Traditional Chinese Medicine Hospital,Puyang Henan 457000,China)

机构地区：[1]濮阳市中医院心内老年病科,河南濮阳457000

出　　处：《临床研究》2024年第9期117-120,共4页Clinical Research

摘　　要：目的探讨冠心病心力衰竭(HF)患者采用保元逐瘀护心汤、雷火灸联合西药治疗的临床效果。方法选取2021年9月至2024年3月濮阳市中医院收治的120例冠心病HF患者,以随机数字表法分成研究组(n=60)与对照组(n=60),对照组采用常规西药治疗,研究组采用保元逐瘀护心汤、雷火灸联合西药治疗,比较两组临床疗效、中医证候积分、心功能指标、N-末端B型脑钠肽前体(NT-proBNP)、运动耐力及不良反应。结果研究组(96.67%)治疗有效率较高于对照组(81.67%),差异具有统计学意义(P<0.05);两组治疗后中医证候积分下降,且研究组低于对照组,差异均有统计学意义(P<0.05);两组治疗后左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)下降,且研究组低于对照组,差异均有统计学意义(P<0.05);两组治疗后NT-proBNP水平下降,且研究组低于对照组,差异均有统计学意义(P<0.05);两组治疗后6 min步行试验(6MWT)步行距离增加,且研究组高于对照组,差异均有统计学意义(P<0.05);研究组不良反应发生率(1.67%)与对照组(5.00%)比较差异无统计学意义(P>0.05)。结论冠心病HF患者采用保元逐瘀护心汤、雷火灸联合西药治疗,能够提高临床疗效,降低血清NT-proBNP水平,改善心功能,提高运动耐力,安全性较高。Objective To investigate the clinical effect of Baoyuan Zhuyu Huxin Decoction and Thunder Fire Moxibustion combined with Western medicine in the treatment of patients with coronary heart disease heart failure(HF).Methods From September 2021 to March 2024,120 patients with coronary heart disease HF were selected from Puyang Traditional Chinese Medicine Hospital.They were randomly divided into a study group(n=60)and a control group(n=60)using a random number table method.The control group received conventional Western medicine treatment,while the study group received Baoyuan Zhuyu Huxin Decoction and Thunder Fire Moxibustion combined with Western medicine treatment.The clinical efficacy,TCM syndrome scores,cardiac function indicators,N-terminal pro-B-type natriuretic peptide(NT-proBNP),exercise tolerance,and adverse reactions were compared between the two groups.Results The treatment efficacy in the study group(96.67%)was higher than that in the control group(81.67%),with statistically significant differences(P<0.05).After treatment,the TCM syndrome scores in both groups decreased,and the scores in the study group were lower than those in the control group,with statistically significant differences(P<0.05).After treatment,the left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)in both groups decreased,and the values in the study group were lower than those in the control group,with statistically significant differences(P<0.05).After treatment,the NT-proBNP levels in both groups decreased,and the levels in the study group were lower than those in the control group,with statistically significant differences(P<0.05).After treatment,the 6-minute walk test(6MWT)walking distance in both groups increased,and the distance in the study group was greater than that in the control group,with statistically significant differences(P<0.05).The incidence of adverse reactions in the study group(1.67%)was not significantly different from that in the control group(5.00%)(P>0.05).Conclusion T

关 键 词：保元逐瘀护心汤 雷火灸 冠心病心力衰竭 

分 类 号：R242[医药卫生—中医临床基础]