Whole-genome Sequencing Reveals Autooctoploidy in Chinese Sturgeon and Its Evolutionary Trajectories  

作　　者：Binzhong Wang Bin Wu Xueqing Liu Yacheng Hu Yao Ming Mingzhou Bai Juanjuan Liu Kan Xiao Qingkai Zeng Jing Yang Hongqi Wang Baifu Guo Chun Tan Zixuan Hu Xun Zhao Yanhong Li Zhen Yue Junpu Mei Wei Jiang Yuanjin Yang Zhiyuan Li Yong Gao Lei Chen Jianbo Jian Hejun Du 

机构地区：[1]Hubei Key Laboratory of Three Gorges Project for Conservation of Fishes,Yichang 443100,China [2]Chinese Sturgeon Research Institute,China Three Gorges Corporation,Yichang 443100,China [3]Yangtze River Biodiversity Research Center,China Three Gorges Corporation,Wuhan 430014,China [4]BGI-Shenzhen,Shenzhen 518083,China [5]BGI Genomics,BGI-Shenzhen,Shenzhen 518083,China [6]Department of Biotechnology and Biomedicine,Technical University of Denmark,Lyngby 2800,Denmark [7]River Basin Complex Administration Center,China Three Gorges Corporation,Yichang 443100,China [8]BGI-Sanya,BGI-Shenzhen,Sanya 572025,China [9]Yangtze Eco-Environment Engineering Research Center,China Three Gorges Corporation,Beijing 100038,China

出　　处：《Genomics, Proteomics & Bioinformatics》2024年第1期51-65,共15页基因组蛋白质组与生物信息学报（英文版）

基　　金：supported by the Three Gorges Environmental Funds of China Three Gorges Corporation(Grant No.XN270)。

摘　　要：The order Acipenseriformes,which includes sturgeons and paddlefishes,represents“living fossils”with complex genomes that are good models for understanding whole-genome duplication(WGD)and ploidy evolution in fishes.Here,we sequenced and assembled the first high-quality chromosome-level genome for the complex octoploid Acipenser sinensis(Chinese sturgeon),a critically endangered species that also represents a poorly understood ploidy group in Acipenseriformes.Our results show that A.sinensis is a complex autooctoploid species containing four kinds of octovalents(8n),a hexavalent(6n),two tetravalents(4n),and a divalent(2n).An analysis taking into account delayed rediploidization reveals that the octoploid genome composition of Chinese sturgeon results from two rounds of homologous WGDs,and further provides insights into the timing of its ploidy evolution.This study provides the first octoploid genome resource of Acipenseriformes for understanding ploidy compositions and evolutionary trajectories of polyploid fishes.

关 键 词：Chinese sturgeon Whole-genome sequencing Autooctoploid Polyploidization and diploidization Whole-genome duplication 

分 类 号：S435.132[农业科学—农业昆虫与害虫防治]