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作 者:刘富[1] 苏静[2] LIU Fu;SU Jing(Daqing Campus Hospital,Harbin Medical University,Daqing 163319,Heilongjiang,China;Department of General Medicine,Daqing People's Hospital,Daqing 163319,Heilongjiang,China)
机构地区:[1]哈尔滨医科大学大庆校区校医院,黑龙江大庆163319 [2]大庆市人民医院全科医学科,黑龙江大庆163319
出 处:《系统医学》2024年第14期35-37,44,共4页Systems Medicine
摘 要:目的分析门冬胰岛素30联合二甲双胍在老年初诊2型糖尿病患者中的应用治疗效果。方法非随机选取2023年4—7月大庆市人民医院收治的68例老年初诊2型糖尿病患者为研究对象,应用治疗方式不同将患者分为对照组(n=34)和研究组(n=34),对照组给予门冬胰岛素30注射治疗,研究组给予门冬胰岛素30联合二甲双胍治疗,比较两组的临床疗效、炎症因子水平和不良反应发生率。结果研究组的有效率为97.06%(33/34),优于对照组的85.29%(29/34),差异有统计学意义(χ^(2)=8.675,P<0.05)。研究组的血糖、血脂水平及炎症因子水平显著优于对照组,差异有统计学意义(P均<0.05)。两组治疗后不良反应发生率比较,差异无统计学意义(P>0.05)。结论门冬胰岛素30联合二甲双胍治疗应用于老年初诊2型糖尿病患者的疗效良好,可以降低患者血糖水平、不良反应发生率。Objective To analyze the therapeutic effect of insulin aspartate 30 combined with metformin in elderly patients with newly diagnosed type 2 diabetes.Methods A total of 68 elderly patients with newly diagnosed type 2 diabetes treated in Daqing People's Hospital from April to July 2023 were non-randomly selected as the study objects.The patients were divided into control group(n=34)and study group(n=34)with different treatment methods.The control group was treated with insulin aspartate 30 injection.The study group was treated with insulin aspartate 30 combined with metformin,and the clinical efficacy,levels of inflammatory factors and incidence of adverse reactions were compared between the two groups.Results The effective rate of the study group was 97.06%(33/34),better than 85.29%(29/34)of the control group,the difference was statistically significant(χ^(2)=8.675,P<0.05).Blood glucose and blood lipid levels of the study group were significantly better than those of the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Insulin aspartate 30 combined with metformin has good efficacy in elderly patients with newly diagnosed type 2 diabetes,and can reduce the blood glucose level and the incidence of adverse reactions.
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