脓毒症患者甲状腺功能变化及其对免疫功能影响机制研究进展  

Progress on mechanism of thyroid dysfunction and its impact on immune function in septic patients

作　　者：曾玉媛 洪少贤 谢凯生 黄育坤[1] Zeng Yuyuan;Hong Shaoxian;Xie Kaisheng;Huang Yukun(Department of Pediatric Intensive Care Unit,Xiamen Children's Hospital(Children's Hospital of Fudan University at Xiamen),Xiamen 361006,China;Department of Cardiology and Cardiovascular Medicine,China Medical University Children's Hospital,Taiwan,China)

机构地区：[1]厦门市儿童医院(复旦大学附属儿科医院厦门医院)儿童重症医学中心,361006 [2]中国医药大学附设儿童医院心血管内科,中国台湾省台中市

出　　处：《中国小儿急救医学》2024年第8期623-627,共5页Chinese Pediatric Emergency Medicine

基　　金：2022年厦门市医疗卫生指导性项目(3502Z20224ZD1277);福建省临床重点专科建设项目(XE2023-ZZYX-C01)。

摘　　要：脓毒症是国内外儿童,尤其是婴幼儿死亡的主要原因之一。脓毒症患者的甲状腺功能存在异常,并影响预后。本文就脓毒症患者体内甲状腺激素和促甲状腺激素水平变化情况、产生原因及甲状腺功能对免疫系统的影响机制作一综述,以期为辅助临床治疗提供新思路。Septic shock is one of the leading causes of death in children,especially infants,both domestically and internationally.Research has found that patients with septic shock often have abnormal thyroid function,which affects their prognosis.This article reviewed the changes in thyroid hormone and thyroid-stimulating hormone levels,the reasons for these changes,and the mechanisms by which thyroid function affects the immune system in patients with septic shock,aiming to provide new ideas for clinical treatment.

关 键 词：甲状腺激素 脓毒症 免疫功能 

分 类 号：R720.597[医药卫生—急诊医学]