芪参益智颗粒定量测定研究  

Study on Quantitative Determination of Qishen Yizhi Granules

作　　者：赵晨阳 王贵金 Chenyang Zhao;Guijin Wang(Hebei Drug Evaluation Center,Shijiashuang Hebei 050000,China;Hebei Province Shijiazhuang Ping An Hospital Co.,LTD.,Shijiazhuang Hebei 050000,China)

机构地区：[1]河北省药品审评中心,河北石家庄050000 [2]河北省石家庄平安医院有限公司,河北石家庄050000

出　　处：《生命科学仪器》2024年第3期29-31,共3页Life Science Instruments

摘　　要：目的探讨芪参益智颗粒中主要组分五味子的定量测定方法。方法用HPLC法测定芪参益智颗粒中五味子醇甲的含量。结果芪参益智颗粒中五味子醇甲的进样量在0.1470~1.1572μg,与峰面积呈良好的线性关系。五味子醇甲的平均回收率为99.45%(n=9),RSD为0.72%。结论用HPLC法测定芪参益智颗粒中主要组分五味子的含量方法简便、准确,回收率与重现性好,可作为该药物的定量测定方法。Objective:To explore the quantitative determination method of Schisandra chinensis,the main component in Qishen Yizhi granules.Methods:The content of schisandrin A in Qishen Yizhi Granules was determined by HPLC.Results:The sample volume of schisandrin A in Qishen Yizhi Granules was 0.1470~1.1572μg,which showed a good linear relationship with the peak area.The average recovery rate of schisandrin A was 99.45%(n=9),and RSD was 0.72%.Conclusion:HPLC method is simple、accurate,with good recovery and reproducibility,and can be used as a quantitative method for the determination of the drug.

关 键 词：芪参益智颗粒 HPLC 定量测定 五味子醇甲 

分 类 号：R927.2[医药卫生—药学]