量化脑功能监测联合脑电双频指数对脑卒中介入取栓术后患者镇静评估的临床分析  

Clinical Analysis of Quantitative Brain Function Monitoring Combined with EEG double-frequency Index

作　　者：黄焱 陆俊才 闭国宁 周美花 Huang Yan;lu Juncai;Bi Guoning;Zhou Meihua(Critical care Department of Jingxi People's Hospital,Jingxi Guangxi 533899,China;Neurosurgery Department of Jingxi People's Hospital,Jingxi Guangxi 533899,China)

机构地区：[1]靖西市人民医院重症医学科,广西靖西533899 [2]靖西市人民医院神经外科,广西靖西533899

出　　处：《生命科学仪器》2024年第3期59-62,共4页Life Science Instruments

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(合同编号Z20211029)。

摘　　要：目的探讨脑卒中介入取栓术后患者镇静评估中应用量化脑功能监测联合脑电双频指数的临床价值。方法选择2021年9月至2024年2月于靖西市人民医院实施介入取栓术治疗的50例脑卒中患者,术后均实施主客观监测,根据监测方案分组,各25例。对照组实施主观监测,选择以格拉斯哥昏迷评分(GCS)、Ramsay评分、RASS评分评价镇静效果,观察组实施主客观监测,在客观评估基础上以量化脑功能监测、脑电双频指数(BIS)评价镇静效果。记录两组评估结果、临床指标、不良事件发生率、药物不良反应发生率、30 d内生存情况。结果两组镇静评估结果显示,观察组Ramsay评分低于对照组,GCS评分、RASS评分、BIS评分、频带能量、α变异率、光谱熵均高于对照组,P<0.05。两组临床指标对比,观察组意识恢复时间、镇痛镇静药物应用剂量、气管导管带管时间、镇静时间、ICU停留时间、总住院时间均比对照组少,P<0.05。两组不良事件发生率对比,观察组发生率低于对照组,P<0.05。两组药物不良反应发生率对比,观察组发生率低于对照组,P<0.05。两组30 d生存情况对比,观察组生存率高于对照组,P<0.05。结论量化脑功能监测联合脑电双频指数对脑卒中介入取栓术后患者镇静评估的价值较高,根据评估结果进行给药,可减少患者镇痛镇静药物的应用剂量,缩短患者恢复时间,并可降低不良事件与不良反应发生率,提高患者30 d内生存率,确保镇静安全性。Objective:To explore the clinical value of quantitative brain function monitoring combined with bispectral index in sedation evaluation of patients with stroke after interventional embolectomy.Methods:From September 2021 to February 2024,50 patients with stroke who were treated by interventional embolectomy in Jingxi People's Hospital were selected.Subjective and objective monitoring was performed after operation,and 25 patients in each group were divided according to the monitoring scheme.The control group was monitored subjectively.Glasgow coma scale(GCS),Ramsay score and RASS score were selected to evaluate the sedation effect,while the observation group was monitored subjectively and objectively.On the basis of objective evaluation,the sedation effect was evaluated by quantitative brain function monitoring and bispectral index(BIS).The evaluation results、clinical indicators、incidence of adverse events、incidence of adverse drug reactions and survival within 30 days were recorded.Results:The results of sedation evaluation in the two groups showed that the Ramsay score in the observation group was lower than that in the control group,while the GCS score、RASS score、BIS score、band energy、αvariation rate and spectral entropy were higher than those in the control group,P<0.05.Compared with the clinical indexes of the two groups、the recovery time of consciousness、the dosage of analgesic and sedative drugs、the time of tracheal intubation、the time of sedation、the stay in ICU and the total hospitalization time in the observation group were less than those in the control group,P<0.05.The incidence of adverse events in the observation group was lower than that in the control group,P<0.05.The incidence of adverse drug reactions in the observation group was lower than that in the control group,P<0.05.Compared with the 30-day survival of the two groups,the survival rate of the observation group was higher than that of the control group,P<0.05.Conclusion:Quantitative brain function monitoring combined

关 键 词：量化脑功能监测 脑电双频指数 脑卒中 介入取栓术 镇静 

分 类 号：R651.1[医药卫生—外科学]