有创-无创序贯性机械通气治疗老年肺内源性急性呼吸窘迫综合征效果分析  

Effect of Invasive-noninvasive Sequential Mechanical Ventilation on Elderly Patients with Pulmonary Endogenous Acute Respiratory Distress Syndrome

作　　者：林耀国 刘卫明 黄雪琴 蔡锦锋 丘雪花 Lin Yaoguo;Liu Weiming;Huang Xueqin;Cai Jinfeng;Qiu Xuehua(Department of Critical Care Medicine Dongguan Dalang Hospital,Dongguan Guangdong 523770,China)

机构地区：[1]东莞市大朗医院重症医学科,广东东莞523770

出　　处：《生命科学仪器》2024年第3期63-65,共3页Life Science Instruments

基　　金：东莞市社会发展科技项目2021年面上项目(20211800902312)。

摘　　要：目的探讨分析有创-无创序贯性机械通气治疗老年肺内源性急性呼吸窘迫综合征(ARDS)患者的临床效果。方法选取2022年1月至2023年9月东莞市大朗医院重症医学科收治的肺内源性ARDS老年患者60例,根据电脑随机法分为对照组(30例)与实验组(30例)。两组均给予气管插管机械通气,对照组采用气管插管或气管切开治疗,实验组采用有创-无创序贯性机械通气治疗。对比两组血气分析指标[包括动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))]、有创机械通气时间、总通气时间、ICU治疗时间、呼吸机相关性肺炎发生率及病死率。结果经过治疗,相比对照组,试验组PaO_(2)水平更高,PaCO_(2)水平更低,P<0.05。相比对照组,试验组进行有创机械通气时间、总通气时间与ICU治疗时间均更短,P<0.05。相比对照组,试验组呼吸机相关性肺炎发生率与病死率对比均更低,P<0.05。结论采用有创-无创序贯性机械通气治疗老年肺内源性ARDS患者效果显著,可改善患者血气分析指标,减轻症状,缩短通气时间与ICU治疗时间,并可降低患者呼吸机相关性肺炎发生率与病死率。Objective:To explore and analyze the clinical effect of invasive-noninvasive sequential mechanical ventilation in the treatment of elderly patients with pulmonary endogenous acute respiratory distress syndrome(ARDS).Methods:From January 2022 to September 2023,60 elderly patients with pulmonary endogenous ARDS admitted to the Department of Critical Care Medicine of Dongguan Da Lang Hospital were randomly divided into control group(30 cases)and experimental group(30 cases).Both groups were given tracheal intubation and mechanical ventilation,while the control group was treated with tracheal intubation or tracheotomy,while the experimental group was treated with invasive-noninvasive sequential mechanical ventilation.The blood gas analysis indexes[including arterial partial pressure of oxygen(PaO_(2))and arterial partial pressure of carbon dioxide(PaCO_(2))]、invasive mechanical ventilation time、total ventilation time、ICU treatment time、incidence and mortality of ventilator-associated pneumonia were compared between the two groups.Results:After treatment,compared with the control group,the PaO_(2) level in the experimental group was higher and the PaCO_(2) level was lower,P<0.05.Compared with the control group,the time of invasive mechanical ventilation、total ventilation and ICU treatment in the experimental group were shorter,P<0.05.Compared with the control group,the incidence and mortality of ventilator-associated pneumonia in the experimental group were lower,P<0.05.Conclusion:Invasive-noninvasive sequential mechanical ventilation is effective in the treatment of elderly patients with pulmonary endogenous ARDS,which can improve blood gas analysis indexes,relieve symptoms,shorten ventilation time and ICU treatment time,and reduce the incidence and mortality of ventilator-associated pneumonia.

关 键 词：老年肺内源性急性呼吸窘迫综合征 有创-无创序贯性机械通气 血气分析指标 

分 类 号：R563[医药卫生—呼吸系统]