高血压患者发生代谢综合征的风险因素分析  

Analysis of Risk Factors for Development of Metabolic Syndrome in Hypertensive Patients

作　　者：韦艳鸿 庞翠军[2] 陈冰 李素媚 WEI Yanhong;PANG Cuijun;CHEN Bing;LI Sumei(Department of Endocrinology and Metabolism,Wuming Hospital of Guangxi Medical University,Nanning 530199,China;Department of Endocrinology and Metabolism,the Second Affiliated Hospital of Guangxi Medical University,Nanning 530000,China)

机构地区：[1]广西医科大学附属武鸣医院内分泌代谢病科,南宁530199 [2]广西医科大学第二附属医院内分泌代谢病科,南宁530000

出　　处：《医学综述》2024年第19期2327-2331,共5页Medical Recapitulate

基　　金：广西医疗卫生适宜技术开发与推广应用项目(S2018041)。

摘　　要：目的分析高血压患者发生代谢综合征的风险因素。方法回顾性分析2023年1-12月在广西医科大学附属武鸣医院建档的120例原发性高血压患者的临床资料,根据患者是否发生代谢综合征分为非代谢综合征组(n=60)和代谢综合征组(n=60)。比较两组患者的临床资料,采用Logistic回归分析高血压患者发生代谢综合征的风险因素。结果代谢综合征组老年、超重、吸烟、饮酒、有高血压家族史、高血压病程>2年、二/三级高血压、高血压管理依从性欠佳的比例高于非代谢综合征组[91.67%(55/60)比71.67%(43/60)、93.33%(56/60)比68.33%(41/60)、85.00%(51/60)比66.67%(40/60)、81.67%(49/60)比65.00%(39/60)、70.00%(42/60)比38.33%(23/60)、96.67%(58/60)比78.33%(47/60)、78.33%(47/60)比58.33%(35/60)、30.00%(18/60)比11.67%(7/60)](P<0.05或P<0.01)。多因素Logistic回归分析结果显示,老年、超重、吸烟、饮酒、有高血压家族史、高血压病程>2年、三级高血压、高血压管理依从性欠佳是高血压患者发生代谢综合征的独立危险因素(OR=6.002,95%CI 1.488~24.202;OR=5.437,95%CI 1.048~28.205;OR=6.655,95%CI 1.599~27.698;OR=3.636,95%CI 1.073~12.316;OR=5.222,95%CI 1.813~15.046;OR=27.143,95%CI 3.134~235.099;OR=24.256,95%CI 1.171~502.278;OR=7.708,95%CI 1.834~32.395)(P<0.05或P<0.01)。结论高血压是代谢综合征的影响因素,临床尤其要注意60岁以上、超重、吸烟、饮酒、有高血压家族史、高血压病程长且分级高、依从性欠佳的高血压患者,他们是代谢综合征的高风险人群。Objective To identify risk factors for metabolic syndrome in hypertensive patients.Methods The clinical data of 120 patients registered in Wuming Hospital of Guangxi Medical University from Jan.to Dec.2023 were included in the retrospective study.According to whether the patient developed metabolic syndrome,they were divided into a non-metabolic syndrome group(n=60)and a metabolic syndrome group(n=60).The clinical data of the two groups were compared,and the risk factors of metabolic syndrome in hypertensive patients were analyzed by Logistic regression.Results The proportions of elderly,overweight,smoking,drinking,family history of hypertension,course of hypertension>2 years,gradeⅡ/Ⅲhypertension,and poor compliance with hypertension management in the metabolic syndrome group were higher than those in the non-metabolic syndrome group[91.67%(55/60)vs 71.67%(43/60),93.33%(56/60)vs 68.33%(41/60),85.00%(51/60)vs 66.67%(40/60),81.67%(49/60)vs 65.00%(39/60),70.00%(42/60)vs 38.33%(23/60),96.67%(58/60)vs 78.33%(47/60),78.33%(47/60)vs 58.33%(35/60),30.00%(18/60)vs 11.67%(7/60)](P<0.05 or P<0.01).Multivariate Logistic regression analysis showed that old age,overweight,smoking,drinking,family history of hypertension,duration of hypertension>2 years,gradeⅢhypertension and poor compliance with hypertension management were independent risk factors for metabolic syndrome in hypertensive patients(OR=6.002,95%CI 1.488-24.202;OR=5.437,95%CI 1.048-28.205;OR=6.655,95%CI 1.599-27.698;OR=3.636,95%CI 1.073-12.316;OR=5.222,95%CI 1.813-15.046;OR=27.143,95%CI 3.134-235.099;OR=24.256,95%CI 1.171-502.278;OR=7.708,95%CI 1.834-32.395)(P<0.05 or P<0.01).Conclusion Hypertension is the influencing factor of metabolic syndrome;especially clinical attention should be paid to hypertensive patients with the features of over 60 years old,overweight,smoking,drinking,family history of hypertension,long hypertension duration and high grade,who are at high risk of metabolic syndrome.

关 键 词：高血压 代谢综合征 风险因素 

分 类 号：R544.1[医药卫生—心血管疾病]