炎性细胞因子与轻度胃肠炎伴婴幼儿良性惊厥相关性的研究进展  

Research Progress of Correlation between Inflammatory Cytokines and Benign Infantile Convulsions with Mild Gastroenteritis

作　　者：高艳萍 高淑青[2] 曲艳杰[3] GAO Yanping;GAO Shuqing;QU Yanjie(Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014000,China;Department of Pediatric Intensive Care Medicine,Baotou Fourth Hospital,Baotou 014000,China;Department of Neonatology,Baotou Fourth Hospital,Baotou 014000,China)

机构地区：[1]内蒙古科技大学包头医学院,内蒙古包头014000 [2]包头市第四医院儿童重症医学科,内蒙古包头014000 [3]包头市第四医院新生儿科,内蒙古包头014000

出　　处：《医学综述》2024年第19期2359-2363,共5页Medical Recapitulate

摘　　要：轻度胃肠炎伴婴幼儿良性惊厥(BICE)是儿科常见疾病,其病因及发病机制复杂。近年来,炎性细胞因子在BICE中的作用受到广泛关注,BICE患儿体内多种炎性细胞因子(白细胞介素-6、γ干扰素、肿瘤坏死因子-α等)的表达水平发生变化,这些变化与肠道炎症反应、免疫失衡及神经系统的异常兴奋密切相关,因此推测这些炎性细胞因子与BICE的发生有关。然而,目前国内外对炎性细胞因子与BICE相关性的研究较少,未来深入研究炎性细胞因子在BICE中的作用机制,有望为该病的临床诊断及治疗提供新的思路。Benign infantile convulsions with mild gastroenteritis(BICE)is a common pediatric disease with complex etiology and pathogenesis.In recent years,the role of inflammatory cytokines in BICE has received widespread attention.The expression levels of various inflammatory cytokines(interleukin-6,interferon gamma,tumor necrosis factor alpha,etc.)change in children with BICE,and these changes are closely related to intestinal inflammation,immune imbalance,and abnormal excitation of the nervous system.Therefore,it is speculated that these inflammatory cytokines are related to the occurrence of BICE.However,there is currently limited research on the correlation between inflammatory cytokines and BICE both domestically and internationally.In the future,in-depth study of the mechanism of action of inflammatory cytokines in BICE is expected to provide new ideas for the clinical diagnosis and treatment of the disease.

关 键 词：轻度胃肠炎 良性惊厥 炎性细胞因子 婴幼儿 

分 类 号：R725.7[医药卫生—儿科]