雄激素对男性神经保护机制的研究进展  

Research progress on the protective mechanism of androgens on male nerves

作　　者：刘雷(综述) 王宝龙(审校)[2] Liu Lei;Wang Baolong(Tianjin Medical University,Tianjin 300052,China;不详)

机构地区：[1]天津医科大学,天津300052 [2]天津医科大学总医院泌尿外科

出　　处：《疑难病杂志》2024年第9期1144-1148,共5页Chinese Journal of Difficult and Complicated Cases

基　　金：天津市卫生健康科技项目(zc20185)。

摘　　要：近年来,阿尔茨海默病、抑郁症、精神分裂症等部分神经系统疾病发病率显著升高,研究发现雄激素对男性神经细胞可能具有减轻炎性反应、抗氧化应激等保护作用,并且部分临床试验结果也表明,雄激素对男性阿尔茨海默病、抑郁症等部分神经系统疾病具有改善认知功能、缓解抑郁症状等效果。因此,学者们对雄激素可能存在的男性神经保护作用机制进行了相关探索,文章就雄激素对男性神经保护作用机制的研究进展作一综述。In recent years,the incidence of some neurological diseases such as Alzheimer's disease,depression and schizophrenia have increased significantly,which has attracted some scholars'attention.Subsequent studies have found that androgens may have protective effects on male nerve cells such as reducing inflammation and anti-oxidative stress.In addition,some clinical trial results also show that androgens can improve cognitive function and alleviate depressive symptoms in some neurological diseases,such as male Alzheimer's disease and depression.Therefore,scholars have explored the possible neuroprotective mechanism of androgens in males.This article reviews the research progress of androgens on the neuroprotective mechanism of males.

关 键 词：雄激素 神经保护 作用机制 男性 

分 类 号：R338[医药卫生—人体生理学]