2011-2022年十堰市发热伴血小板减少综合征流行特征及核酸检测分析  

Epidemiological characteristics and nuclear acid detection of severe fever with thrombocytopenia syndrome in Shiyan in 2011-2022

作　　者：梅玉发[1] 崔龙[1] 黄强 陈红霞[2] MEI Yufa;CUI Long;HUANG Qiang;CHENG Hongxia(Shiyan Center for Disease Control and Prevention,Shiyan,Hubei 442000,China;Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei 442000,China)

机构地区：[1]湖北省十堰市疾病预防控制中心,湖北十堰442000 [2]湖北医药学院附属太和医院,湖北十堰442000

出　　处：《公共卫生与预防医学》2024年第5期101-104,共4页Journal of Public Health and Preventive Medicine

基　　金：十堰市太和医院博士后基金项目(2017GXL-013)。

摘　　要：目的分析十堰市发热伴血小板减少综合征(severe fever with thrombocytopenia syndrome,SFTS)的监测结果,为SFTS防控提供科学依据。方法采用描述性流行病学方法对监测数据进行流行病学特征分析,采用Real time RT-PCR法开展病例SFTSV核酸检测分析。结果2011—2022年十堰市共报告SFTS确诊病例54例,死亡5例(病死率为9.26%)。病例集中在3~10月,4~8月为发病高峰(85.18%)。50岁以上中老年为高发人群(94.44%),农民为高危职业(92.59%),男女性别比为0.64∶1。北三县(丹江口市、郧阳区、郧西县)为高发地区(90.74%)。发病后7 d内采样与8~11 d采样,二者阳性率差异无统计学意义(66.67%,57.14%)(Fisher精确概率法,P=0.674)。结论十堰市SFTS发病以散发为主,以中老年农民为主,具有明显的季节性和地区性,应强化病媒管理,强化高危人群的健康教育、SFTS病例诊断报告与标本采集送检管理,加大对北三县的防控力度。Objective To analyze the monitoring results of severe fever with thrombocytopenia syndrome(SFTS)in Shiyan,Hubei province,and to provide a scientific basis for the prevention and control of SFTS.Methods Descriptive epidemiological analysis was conducted on the surveillance data of SFTS,and real-time PCR was performed for detecting SFTSV RNA.Results A total of 54 laboratory-confirmed cases of SFTS were reported in Shiyan from 2011 to 2022,including 5 deaths(9.26%).The cases mainly occurred in March to October,with a peak in April to August(85.18%).People over 50 years old were the high-risk group(94.44%),and farmers were the high-risk occupation(92.59%).The male to female sex ratio was 0.64∶1.The three northern counties(Danjiangkou City,Yunyang District,and Yunxi County)were high-incidence areas(90.74%).There was no statistical difference in the positive rates of sampling between within 7 days and 8-11 days after onset(66.67%vs.57.14%)(Fisher′s precision probability test,P=0.674).Conclusion The incidence of SFTS in Shiyan is mainly sporadic,dominated by middle-aged and elderly people and farmers,and shows obvious seasonal and regional characteristics.It is necessary to strengthen vector management,health education,SFTS case reporting and sample collection,and inspection management of high-risk groups,and increase prevention and control efforts in the three northern counties of Shiyan.

关 键 词：发热伴血小板减少综合征 流行病学特征 核酸检测 

分 类 号：R181[医药卫生—流行病学]