查耳酮衍生物改性的硅油包水型乳化剂的制备与性能  

Preparation and properties of water-in silicone emulsifier modified by Chalcone derivative

作　　者：陈凤凤 吴凡 刘春环 杨成 CHEN Fengfeng;WU Fan;LIU Chunhuan;YANG Cheng(School of Chemical and Material Engineering,Jiangnan University,Wuxi 214026,Jiangsu,China;Key Laboratory of Synthesis and Biocolloids,Ministry of Education,Wuxi 214026,Jiangsu,China)

机构地区：[1]江南大学化学与材料工程学院,江苏无锡214026 [2]合成与生物胶体教育部重点实验室,江苏无锡214026

出　　处：《精细化工》2024年第9期1958-1965,共8页Fine Chemicals

基　　金：中国博士后科学基金面上资助项目(2021M701464)。

摘　　要：将查耳酮衍生物〔(E)-3-(4-烯丙氧基)苯基-1-(4-甲氧基苯基)丙-2-烯-1-酮〕(Methoxy-Cha)与烯丙基聚乙二醇(APEG-400)共同接枝到含氢硅油(含氢量0.18%)链上,合成了具有紫外吸收性能的硅油包水(W/Si)型乳化剂EMCD。以EMCD为乳化剂、6黏度硅油为主油相,制备了EMCD稳定的硅油包水乳液,采用1HNMR表征了EMCD的化学结构,考察了不同EMCD质量分数和m(6黏度硅油)∶m(水)对乳液粒径、稳定性和流变性能的影响,测试了EMCD与亚甲基双-苯并三唑基四甲基丁基酚(MBBT)复配的协同增效效果,并测试了EMCD用于防晒乳液的防晒指数(SPF)。结果表明,当m(6黏度硅油)∶m(水)在25.0∶75.0~17.5∶82.5范围内,w(EMCD)=2.0%~3.0%时,EMCD稳定的硅油包水乳液稳定性和流变性能最佳。w(EMCD)=3.0%和w(MBBT)=2.0%复配后总体吸收的协同增效率最高,达5.24%。与KF-6017乳化剂相比,EMCD能使防晒乳液的体外SPF从21.76提升至33.29,UVA/UVB从0.433提升至0.587,EMCD增强了防晒乳液的广谱防护能力。Water-in silicone(W/Si)emulsifier(EMCD)with UV absorption capacity was prepared by grafting Chalcone derivative(E)-3-(4-allyloxygen)phenyl-1-(4-methoxyphenyl)propyl-2-alkene-1-ketone(Methoxy-Cha)and allyl polyethylene glycol(APEG-400)onto hydrogen-containing silicone oil(0.18%hydrogen content)chains.EMCD stabilized water-in-silicone emulsion was then synthesized using EMCD as emulsifier and 6 viscosity silicone oil as main oil phase.1HNMR was used to characterize the chemical structure of EMCD,and the influence EMCD mass fraction and m(6 viscosity ilicone oil)∶m(water)on the particle size,stability and rheological properties of emulsion were investigated.The synergistic effect of EMCD combined with methylene bis-benzotriazolyl tetramethylbutylphenol(MBBT)and the sun protection factor(SPF)of sunscreen lotion with EMCD added were explored and analyzed.The results showed that,when m(6 viscosity silicone oil)∶m(water)was in the range of 25.0∶75.0~17.5∶82.5 and w(EMCD)=2.0%~3.0%,EMCD stabilized water-in-silicone emulsion exhibited the best stability and rheological properties.The synergistic efficiency reached the highest up to 5.24%when EMCD and MBBT combined at w(EMCD)=3.0%and w(MBBT)=2.0%.Compared with KF-6017 emulsifier,EMCD could increase the in vitro SPF of the sunscreen lotion from 21.76 to 33.29,and UVA/UVB from 0.433 to 0.587,while EMCD enhanced the broad spectrum protection ability of sunscreen lotion.

关 键 词：查耳酮 聚硅氧烷乳化剂 硅油包水乳液 稳定性 协同增效 表面活性剂 

分 类 号：TQ423[化学工程] TQ628