2020-2023年章丘区产妇乙肝表面抗原检测及新生儿首剂乙肝疫苗接种情况  

Detection of Hepatitis B Surface Antigen in Puerpera and the First Dose of Hepatitis B Vaccine for Newborns in Zhangqiu District from 2020 to 2023

作　　者：李宝珍 LI Baozhen(Department of Immunology and Prevention,Zhangqiu District Center for Disease Control and Prevention,Jinan 250200,Shandong,China)

机构地区：[1]济南市章丘区疾病预防控制中心免疫预防科,山东济南250200

出　　处：《中国卫生产业》2024年第9期216-219,共4页China Health Industry

摘　　要：目的了解济南市章丘区产妇乙型肝炎(简称乙肝)表面抗原(Hepatitis B Surface Antigen,HBsAg)阳性率及新生儿首剂乙型肝炎疫苗(Hepatitis B1 Vaccine,HepB1)接种情况。方法收集2020—2023年济南市章丘区3家医疗产科机构产妇的HBsAg检测结果、新生儿HepB1接种率、及时接种率和未及时接种原因,进行描述性分析。结果2020—2023年共登记产妇23984人,HBsAg检测率为99.99%(23982/23984),HBsAg阳性率为2.14%(514/23982)。新生儿HepB1及时接种率为93.55%(22439/23986)。HBsAg阳性母亲所生新生儿HepB1及时接种率为93.58%(481/514),乙肝免疫球蛋白(Hepatitis B immune Globulin,HBIG)及时接种率为97.47%(501/514)。乙肝病毒e蛋白抗原阳性母亲所生新生儿HepB1及时接种率为94.44%(153/162),HBIG及时接种率为97.53%(158/162)。乙肝疫苗因早产、新生儿肺炎、出生低体重、缺氧等导致未及时接种。结论济南市章丘区产妇HBsAg阳性率较低,阳性母亲所生新生儿HepB1及时接种率和联合免疫接种率有待提高,应继续加强实施母婴传播的阻断措施,进一步提高新生儿HepB1及时接种率和联合免疫接种率。Objective To understand the positive rate of hepatitis B surface antigen(HBsAg)in puerpera and the first dose of hepatitis B vaccine(HepB1)in newborns in Zhangqiu District of Jinan.Methods The HBsAg detection results,neonatal HepB1 vaccination rate,timely vaccination rate and reasons for non-timely vaccination of puerpera were collected from 3 medical obstetric institutions in Zhangqiu District of Jinan from 2020 to 2023,and descriptive analysis was conducted.Results A total of 23984 puerpera were registered from 2020 to 2023,the HBsAg detection rate was 99.99%(23982/23984),and the positive rate of HBsAg was 2.14%(514/23982).The timely vaccination rate of neonatal HepB1 was 93.55%(22439/23986).The immunization rate of HepB1 and Hepatitis B immune Globulin(HBIG)were 93.58%(481/514)and 97.47%(501/514)respectively in newborns with HBsAg positive mothers.Human Hepatitis Be Antigen positive mothers had 94.44%(153/162)timely vaccination rates for HepB1 and 97.53%(158/162)for HBIG.Hepatitis B vaccine was not given in time due to premature delivery,neonatal pneumonia,low birth weight and hypoxia.Conclusion The positive rate of HBsAg in postpartum women in Zhangqiu District of Jinan is low.The timely vaccination rate and combined immunization rate of HepB1 in children born to positive mothers need to be improved.It is necessary to continue to strengthen the implementation of measures to block mother to child transmission and further increase the timely vaccination rate and combined immunization rate of HepB1 in newborns.

关 键 词：产妇 乙型肝炎表面抗原 新生儿 乙肝疫苗 

分 类 号：R392[医药卫生—免疫学]