Effect of reaction and post-treatment conditions on physico-chemical properties of magnetic iron oxide nano-particles Author links open overlay panel  

作　　者：Masome Moeni Mohamed Edokali Matthew Rogers Oscar Cespedes Louey Tliba Tamseela Habib Robert Menzel Ali Hassanpour 

机构地区：[1]School of Chemical and Process Engineering,Faculty of Engineering and Physical Science,University of Leeds,Leeds,LS29JT,UK [2]School of Physics and Astronomy,Faculty of Engineering and Physical Science,University of Leeds,Leeds,LS29JT,UK [3]Mechanical Engineering Department,University of Engineering&Technology,Lahore,Pakistan [4]School of Chemistry,Faculty of Engineering and Physical Science,University of Leeds,Leeds,LS29JT,UK

出　　处：《Particuology》2024年第8期155-167,共13页颗粒学报（英文版）

摘　　要：Poor stability and dispersibility,as well as aggregation are considered as major challenges in clinical application of iron oxide nanoparticles(IONPs).Several studies have shown that the synthesis parameters and post-synthesis treatments e.g.,drying methods,have the capability to improve the particles'characteristics.Herein,we investigate the combined effect of synthesis and post-treatment parameters on the particle size,stability and magnetism of IONPs.Magnetite(Fe_(3)O_(4))NPs were prepared via co-precipitation and post-treated using different methods,i.e.(i)freeze dried at-53℃,0.133 mbar for 48 h(liquid nitrogen frozen(LFD)and freezer frozen(FFD)),(ii)vacuum oven dried(VOD)at 60℃for 24 h,and(iii)kept wet colloidal(WET),dispersed in deionized water.The Fe_(3)O_(4)NPs’chemical functional groups,size,shape,crystallinity,stability,aggregation,porosity,and magnetic properties were further analysed using different characterisation techniques.Analytical results showed that,while the WET sample had the best stability and significantly less aggregation at different temperatures,amongst post-treated Fe_(3)O_(4)NPs,LFD sample exhibited the best stability(up to 37℃),dispersion and smallest polydispersity index.Furthermore,all dried NPs had superparamagnetic characteristics,while,LFD Fe_(3)O_(4)NPs had better magnetic properties and stability than other drying methods.

关 键 词：Iron oxide nanoparticles CO-PRECIPITATION Stability Aggregation Magnetic properties 

分 类 号：TB383[一般工业技术—材料科学与工程]