苍附导痰汤加味治疗脾虚痰湿型多囊卵巢综合征伴胰岛素抵抗临床观察  

Efficacy observation of modified Cangfu Daotan decoction on polycystic ovary syndrome with insulin resistance and syndrome of phlegm-dampness due to deficiency of spleen

作　　者：张雨雨 薛勤梅[2] ZHANG Yu-yu;XUE Qin-mei(Shanxi University of Traditional Chinese Medicine,Taiyuan 030024,China;不详)

机构地区：[1]山西中医药大学,太原030024 [2]山西省中医院

出　　处：《山西中医》2024年第9期22-24,共3页Shanxi Journal of Traditional Chinese Medicine

摘　　要：目的:观察苍附导痰汤加味治疗脾虚痰湿型多囊卵巢综合征伴胰岛素抵抗的临床疗效。方法:将80例多囊卵巢综合征伴胰岛素抵抗患者按随机数字表法分为两组各40例,对照组予二甲双胍治疗,治疗组在对照组基础上加苍附导痰汤加味治疗。两组均治疗3个月经周期,比较两组临床疗效。结果:治疗组总有效率为92.5%,对照组为87.5%,两组比较,差异有统计学意义(P﹤0.05)。治疗后,治疗组胰岛素抵抗相关指标、中医证候评分、子宫内膜容受性相关指标、性激素水平(PRL、FSH、LH、T)、总胆固醇(TC)、甘油三酯(TG)水平均较对照组改善明显,差异有统计学意义(P﹤0.05)。结论:苍附导痰汤加味治疗脾虚痰湿型多囊卵巢综合征伴胰岛素抵抗患者,可以缓解临床症状,一定程度上纠正胰岛素抵抗状态,调节性激素水平。Objective:To observe the clinical efficacy of modified Cangfu Daotan decoction on polycystic ovary syndrome with insulin resistance and syndrome of phlegm-dampness due to deficiency of spleen.Methods:80 cases of patients with polycystic ovary syndrome with insulin resistance were randomly divided into two groups,40 cases in each group.The control group was treated with metformin,while the treatment group was treated plus with modified Cangfu Daotan decoction on the basis of control group.Both groups were treated for 3 menstrual cycles.The clinical effcacy of patients was compared between two groups.Results:The total effective rate was 92.5%in the treatment group and 87.5%in the control group respectively,and the comparative difference between two groups was statistically significant(P﹤0.05).In the treatment group after treatment,insulin resistance-related indexes,TCM syndrome score,endometrial receptivity-related indexes,sex hormone levels(PRL,FSH,LH,T),total cholesterol(TC)and triglyceride(TG)were significantly improved compared with in the control group,and the difference was statistically significant(P﹤0.05).Conclusion:Modified Cangfu Daotan decoction for treating polycystic ovary syndrome with insulin resistance and syndrome of phlegm-dampness due to deficiency of spleen can relieve the clinical symptoms,correct the state of insulin resistance to a certain extent and regulate the level of sex hormones.

关 键 词：多囊卵巢综合征 胰岛素抵抗 脾虚痰湿 苍附导痰汤加味 中医药疗法 

分 类 号：R711.75[医药卫生—妇产科学]