Mondini畸形婴幼儿人工耳蜗术后听觉能力长期随访研究  

Long-term Follow-up Study of Auditory Performance after Cochlear Implantation in Infants and Toddlers with Mondini Deformity

作　　者：张李芳 孟超[2] 郭倩倩[2] 孔颖[2] 吕静[2] 董瑞娟[2] 李玉玲[2] 亓贝尔[2] 王硕 魏兴梅 陆思萌 薛书锦 高振橙 陈雪清[2,3] 李永新 ZHANG Li-fang;MENG Chao;GUO Qian-qian;KONG Ying;LV Jing;DONG Rui-juan;LI Yu-ling;QI Bei-er;WANG Shuo;WEI Xing-mei;LU Si-meng;XUE Shu-jin;GAO Zhen-cheng;CHEN Xue-qing;Li Yong-xin

机构地区：[1]北京社会管理职业学院(民政部培训中心),北京102600 [2]首都医科大学附属北京同仁医院神经耳科,北京100730 [3]首都医科大学附属北京同仁医院/北京市耳鼻咽喉科研究所/首都医科大学耳鼻咽喉头颈科学教育部重点实验室,北京100730 [4]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,北京100730

出　　处：《中国听力语言康复科学杂志》2024年第5期460-464,共5页Chinese Scientific Journal of Hearing and Speech Rehabilitation

摘　　要：目的探讨0~3岁Mondini畸形患儿人工耳蜗(CI)术后5年听觉能力发展规律。方法采用回顾性队列研究设计,共纳入235例36个月龄以内接受单侧CI手术患儿。根据影像学检查结果,分为Mondini组(47例)和内耳结构正常的对照组(188例)。由经过统一培训的专业人员使用听觉能力分级(CAP)量表评估受试者听觉能力。分别在CI术前及开机后1、2、3、6、9、12、18、24、30、36、42、48、54、60个月时进行评估。结果两组患儿CAP得分在CI术前及开机1个月时存在显著差异(P<0.05),其余各随访时间点均无显著差异(P>0.05)。在开机42、48、54、60个月时,两组患儿CAP得分均接近7分。Mondini组患儿CAP得分术前与开机后1、2、3、6、9、12、18、24、30、36、42、48、54、60个月均存在显著差异(P<0.05);在开机1年内,开机1个月与3个月、2个月与3个月、3个月与9个月、6个月与9个月、9个月与18个月之间均存在显著差异(P<0.05);而在开机1~3年,开12个月与24个月、18个月与24个月、24个月与36个月、30个月与42个月均存在显著差异(P<0.05);在开机3年后各随访时间点间均不存在显著差异(P>0.05)。结论CI可有效改善Mondini畸形患儿的听觉能力,患儿在CI术后3年内听觉能力有显著提高。此外,Mondini畸形患儿在CI术后听觉能力的提高与内耳结构正常的患儿表现相似。Objective To investigate the development of auditory performance in children with Mondini malformation aged 0-3 years within 5 years after cochlear implantation(CI).Methods A retrospective cohort study design was used in this study,and a total of 235 children who underwent unilateral CI surgery within 36 months of age were included.Based on the imaging findings,they were divided into Mondini group(47 cases)and control group with normal inner ear structure(188 cases).Auditory performance was assessed by the same group of uniformly standardized trained professionals using the Categories of auditory performance(CAP)scale.The assessment was performed before CI and at 1,2,3,6,9,12,18,24,30,36,42,48,54,and 60 months after switch-on,respectively.Results The CAP scores of the two groups were significantly different at pre-CI and at 1 month after switch on(P<0.05),and there were no significant differences at the rest of the follow-up time points(P>0.05).At 42 months,48 months,54 months,and 60 months after start-up,the CAP scores of the children in both groups were close to 7.There was a significant difference between the preoperative CAP scores and the CAP scores at 1,2,3,6,9,12,18,24,30,36,42,48,54,and 60 months after start-up in the Mondini group(P<0.05).Within 1 year of switch-on,significant differences were found between 1 month after switch-on and 3 months after switch-on,2 months after switch-on and 3 months after switch-on,3 months after switch-on and 9 months after switch-on,6 months after switch-on and 9 months after switch-on,and 9 months after switch-on and 18 months after switch-on(P<0.05);whereas between 1 year and 3 years after switch-on,12 months after switch-on and 24 months after switch-on,18 months after switch-on and 24 months after switch-on,24 months after switch-on and 36 months after switch-on,30 months after switch-on and 42 months after switch-on were significantly different(P<0.05);and there were no differences between the follow-up time points after 3 years of switch-on(P>0.05).Conclusion Cochle

关 键 词：MONDINI畸形 人工耳蜗植入 听觉能力分级 

分 类 号：R76[医药卫生—耳鼻咽喉科]