Illuminating functions of evolutionarily conserved long non-coding RNAs  

作　　者：Ruiqiao He Fangqing Zhao 

机构地区：[1]Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China [2]Key Laboratory of Systems Health Science of Zhejiang Province,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024,China

出　　处：《Science China(Life Sciences)》2024年第9期2043-2044,共2页中国科学（生命科学英文版）

摘　　要：Long non-coding RNAs(lnc RNAs)serve as crucial regulators of gene expression,influencing various physiological processes and disease states(Cabili et al.,2011;Ulitsky and Bartel,2013;Yao et al.,2019).Dysregulation of certain notable lnc RNAs,such as HOTAIR and MALAT1,has been implicated in a wide range of pathological processes,including tumorigenesis in various human cancers(Gupta et al.,2010;Kim et al.,2018).However,the functions of the majority of lnc RNAs remain elusive.

关 键 词：MALAT1 HOTAIR 

分 类 号：Q75[生物学—分子生物学]