Electrochemical Cascade Annulation for the Synthesis of 3-Sulfanylquinoline Derivatives under Mild Conditions  

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作  者:Ke Li Ming-Zhong Guo Zhuo Chen Hao-Ran Li Weisi Guo Ming Li Lin-Bao Zhang 

机构地区:[1]State Key Laboratory Base of Eco-Chemical Engineering,College of Chemistry and Molecular Engineering,Qingdao University of Science&Technology,Qingdao,Shandong 266042,China

出  处:《Chinese Journal of Chemistry》2024年第16期1833-1838,共6页中国化学(英文版)

基  金:supported by the National Natural Science Foundation of China(21801152 and 21572110);the Youth Innovation Science and Technology Plan of Colleges and Universities in Shandong Province(2021KJ076).

摘  要:An efficient electrochemical approach has been developed for the construction of 3-sulfanylquinoline derivatives by treating phenylethynylbenzoxazinanones with disulfides in an undivided cell.The protocol provided a convenient route to functionalized quinolines with good functional group tolerance.Moreover,it does not require any metal catalysts or additives,furnishing a series of biologicalquinolines inmoderatetogoodyields.

关 键 词:ELECTROCATALYSIS ELECTROOXIDATION ANNULATION 3-Sulfany QUINOLINE C3-thioetherification 

分 类 号:O646[理学—物理化学]

 

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