睾丸衰老影响全身健康的研究进展  

Impacts of testis aging on overall health:Advances in studies

作　　者：曹芮 邹和德 陈文康 赵家有[2] CAO Rui;ZOU He-de;CHEN Wen-kang;ZHAO Jia-you(Graduate School,Hebei University of Chinese Medicine,Shijiazhuang,Hebei 050091,China;Graduate School,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]河北中医药大学研究生院,河北石家庄050091 [2]中国中医科学院研究生院,北京100700

出　　处：《中华男科学杂志》2024年第7期658-662,共5页National Journal of Andrology

基　　金：国家自然科学基金(82274337);首都卫生发展科研专项(首发2022-2-4271);中国中医科学院科技创新工程课题资助(CI2023C018YL)。

摘　　要：睾丸具有分泌雄激素和产生精子两大功能,是男性重要的生殖器官之一。雄激素及生精功能是睾丸功能的评价要素,雄激素缺乏或生精功能减退既是睾丸衰老的标志性表现,也是睾丸衰老的“产物”。为更好研究阐释睾丸衰老与全身健康的关系,本文以雄激素缺乏与各系统疾病关系为主线梳理相关文献,认为睾丸衰老通过不同渠道影响心血管系统、神经系统的健康及影响着代谢性疾病、骨科疾病、前列腺癌、肾病、消化性溃疡等疾病的发生发展,提示我们要关注男性生殖健康及其对全身健康的影响,为临床诊疗提供新的思考和借鉴。The testis,as one of the important reproductive organs in men,has two major functions of secreting androgens and producing sperm.Androgen and spermatogenesis are the key factors for the evaluation of the testicular function.The lack of androgen or the decline of spermatogenic function is both a symbolic manifestation and a"product"of testis aging.In order to gain a deeper insight into the relationship between testis aging and overall health,this article reviews the relevant literature based on the correlation of androgen deficiency with various systemic diseases and the belief in the impacts of testis aging on the health of the cardiovascular and nervous systems through different channels,the development and progression of metabolic diseases,orthopedic diseases,PCa,kidney disease,peptic ulcer and other diseases.All these suggest that adequate attention should be paid to the studies of male reproductive health and its impact on overall health,so as to provide some new ideas and evidence for clinical diagnosis and treatment of relevant conditions.

关 键 词：睾丸衰老 雄激素类 研究进展 

分 类 号：R697.22[医药卫生—泌尿科学]