乳酸菌发酵物的美白效果研究  

Study on Whitening Effect of Lactobacillus Fermentation

作　　者：王燕亭 许智鹏 陈煜沛 王贵弘 Wang Yanting;Xu Zhipeng;Chen Yupei;Wang Guihong(Xiamen Medical College,Xiamen 361023,China;Engineering Research Center of Natural Cosmeceuticals College of Fujian Province,Xiamen 361023,China)

机构地区：[1]厦门医学院,福建厦门361023 [2]天然化妆品福建省高校工程研究中心,福建厦门361023

出　　处：《广东化工》2024年第15期62-64,共3页Guangdong Chemical Industry

基　　金：福建省中青年教师教育科研项目(JAT200723);厦门医学院科技计划项目(K2023-30)。

摘　　要：探究乳酸菌(菌株:Lactobacillus sp.)发酵物在动物模型上的美白效果。采用MTT测试和蘑菇酪氨酸酶活性抑制试验分析发酵物的细胞毒性及对酪氨酸酶活性的抑制效果;选取雌性C57BL/6小鼠建模动物模型,CK仪器测量用药前后小鼠耳部皮肤的黑色素含量,并与凡士林、熊果苷的美白效果参照对比。结果表明,乳酸菌(菌株:Lactobacillus sp.)发酵物具有天然、低毒、易提取的特点,且对酪氨酸酶活性有较好的抑制作用,能有效降低小鼠耳部皮肤黑色素指数,对动物模型具有较好的美白作用。To explore the whitening effect of lactic acid bacteria fermentation in the animal model(strain:Lactobacillus sp.).The cytotoxicity of the fermentation was analyzed by MTT test,and the inhibitory effect of mushroom tyrosinase activity was analyzed by mushroom tyrosinase activity inhibition test.Female C57BL/6 mice were selected to build an animal model.The melanin content of ear skin of mice before and after treatment was measured by CK instrument,and the whitening effect was compared with that of Vaseline and arbutin.The results showed that Lactobacillus sp.Fermentation has the characteristics of natural,low toxicity and easy extraction,and has a good inhibitory effect on tyrosinase activity,can effectively reduce the melanin index of ear skin of mice,and has a good whitening effect on animal models.

关 键 词：乳酸菌发酵物 动物模型 黑色素 美白 酪氨酸酶抑制剂 

分 类 号：TQ[化学工程]