主动脉峡部血流指数及血清CysC对妊娠期糖尿病胎儿心功能的评价及围产儿结局的评估价值  

The value of aortic isthmus blood flow index and serum CysC in evaluating cardiac function and perinatal outcome of fetus with gestational diabetes mellitus

作　　者：蒋爱清[1] 陈飞[1] 杨鹤 JIANG Aiqing;CHEN Fei;YANG He(Department of Ultrasound,Bozhou People's Hospital,Bozhou Anhui 236800,China;Department of Gynecology and obstetrics,Bozhou People's Hospital,Bozhou Anhui 236800,China)

机构地区：[1]亳州市人民医院超声科,安徽亳州236800 [2]亳州市人民医院妇产科,安徽亳州236800

出　　处：《中国妇产科临床杂志》2024年第5期442-444,共3页Chinese Journal of Clinical Obstetrics and Gynecology

基　　金：2021年亳州市科委重点研发计划(bzzc2021053)。

摘　　要：目的探讨主动脉峡部血流指数(IFI)及血清胱抑素C(CysC)对妊娠期糖尿病(GDM)胎儿心功能的评价及围产儿结局的评估价值。方法回顾性分析2021年3月至2022年12月亳州市人民医院接诊的103例GDM患者的临床资料作为观察组,并选择本院同期88例身体健康的妊娠中期孕妇作为对照组。比较两组的IFI、CysC、等容舒张时间(IRT)、等容收缩时间(ICT)、射血时间(ET)的表达水平,记录两组围产儿结局。采用Pearson相关分析法分析IFI、血清CysC与IRT、ICT、ET的相关性。结果观察组IFI、ET水平低于对照组,CysC、IRT、ICT水平均高于对照组(P<0.05);经Pearson相关分析结果显示,IFI水平与IRT、ICT均呈负相关,IFI水平与ET呈正相关,血清CysC水平与ET呈负相关,血清CysC水平与IRT、ICT、ET均呈正相关(P<0.05);观察组围产儿不良结局总发生率高于对照组(P<0.05);不良结局组IFI水平低于良好结局组,CysC水平高于良好结局组(P<0.05)。结论IFI及血清CysC对GDM胎儿心功能及围产儿结局的具有一定的评估价值。Objective To investigate the value of aortic isthmus blood flow index(IFI)and serum cystatin C(CysC)in the evaluation of fetal cardiac function and perinatal outcome in gestational diabetes mellitus(GDM).Methods The clinical data of 103 GDM patients seen in Bozhou People's hospital from March 2021 to December 2022 were retrospectively analyzed and studied as an observation group,and 88 healthy mid-gestation pregnant women in the same period were selected as a control group.The expression levels of IFI,CysC,isovolumic diastolic time(IRT),isovolumic contraction time(ICT),and ejection time(ET)were compared between the two groups,and the perinatal outcomes of the two groups were recorded.Pearson correlation analysis was used to analyze the correlation between IFI,serum CysC and IRT,ICT and ET.Results The levels of IFI and ET in the observation group were lower than those in the control group,and the levels of CysC,IRT,and ICT were higher than those in the control group(P<0.05);the results of Pearson's correlation analysis showed that the levels of IFI were negatively correlated with IRT and ICT,the levels of IFI were positively correlated with ET,the levels of serum CysC were negatively correlated with ET,and the levels of serum CysC and IRT,ICT and ET were positively correlated(P<0.05);the total incidence of perinatal adverse outcomes in the observation group was higher than that in the control group(P<0.05);the level of IFI in the adverse outcome group was lower than that in the group with a good outcome,and the level of CysC was higher than that in the group with a good outcome(P<0.05).Conclusion IFI and serum CysC have a certain value in the evaluation of fetal heart function and perinatal outcome of GDM.

关 键 词：妊娠期糖尿病 主动脉峡部血流指数 胱抑素C 胎儿心功能 围产儿结局 

分 类 号：R714.256[医药卫生—妇产科学]