调神解郁飞针呼吸补泻埋线法治疗轻中度肝郁脾虚型抑郁症  

Treatment of Mild to Moderate Depression of Liver Stagnation and Spleen Deficiency Type Using Spirit Regulating and Depression Resolving Flying Acupuncture with Respiratory Supplementation and Draining Method and Catgut Embedment in Acupoint

作　　者：余丹 马瑞华 王新义 YU Dan;MA Ruihua;WANG Xinyi(Zhumadian Second People's Hospital,Affiliated Brain Disease Hospital of Zhengzhou University,Zhumadian 463000,China;Beijing Huilongguan Hospital,Peking University Huilongguan Clinical Medical College,Beijing 100096,China;Henan Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Zhengzhou 450000,China)

机构地区：[1]驻马店市第二人民医院,郑州大学附属脑病医院,河南驻马店463000 [2]北京回龙观医院,北京大学回龙观临床医学院,北京100096 [3]河南省中西医结合医院,河南郑州450000

出　　处：《中医药信息》2024年第9期60-65,共6页Information on Traditional Chinese Medicine

基　　金：河南中医药拔尖人才培养项目(豫中医科教〔2018〕35号)。

摘　　要：目的:观察调神解郁飞针呼吸补泻埋线法联合选择性5-羟色胺再摄取抑制剂(SSRIs)类药物治疗肝郁脾虚型抑郁症的临床疗效。方法:选取符合纳入标准的轻中度抑郁症患者80例,依据随机数字表随机分为对照组和治疗组,每组各40例,治疗过程中对照组和治疗组各脱落2例。两组患者均给予SSRIs类药物口服治疗,对照组在口服SSRIs类药物的基础上加用电针治疗,治疗组在口服SSRIs类药物的基础上加用飞针呼吸补泻埋线法治疗,两组均治疗4周。比较两组患者治疗1、2、3、4周末汉密顿抑郁量表(HAMD)、汉密顿焦虑量表(HAMA)、临床疗效总评量表(CGI)的评分情况,并比较临床疗效。结果:治疗后,两组患者HAMD、HAMA评分均降低(P<0.01);与对照组比较,治疗组HAMD评分在治疗2、3、4周末时降低更明显(P<0.05,P<0.01);治疗组HAMA评分在治疗3、4周末时降低更明显(P<0.01)。治疗后,两组患者CGI评分均下降(P<0.01),且治疗组治疗1、2、3、4周末较对照组CGI评分下降明显(P<0.01);治疗后,治疗组总有效率100%(38/38),显著高于对照组89.47%(31/38)(P<0.01)。结论:调神解郁飞针呼吸补泻埋线法联合SSRIs类药物可以有效改善肝郁脾虚型轻中度抑郁症患者的抑郁及焦虑情绪。Objective:To observe the clinical efficacy of combining the spirit regulating and depression resolving flying acupuncture with respiratory supplementation and draining method and catgut embedment in acupoints with Selective Serotonin Reuptake Inhibitors(SSRIs)for treating mild to moderate depression of experimental and control groups,along with clinical efficacy.Results:Compared with healthy volunteers,SLE women had significantly lower levels of AMH,INHB,and E_(2),and significantly higher levels of FSH and LH,with statistical significance(P<0.05,P<0.01).After treatment,compared to the control group,the experimental group showed a significant increase in AMH,INHB levels,and endometrial thickness(P<0.01)and a significant decrease in FSH levels(P<0.01).TCM syndrome scores and SLEDAI scores significantly decreased,and complement C3 levels significantly increased(P<0.01).There were no statistically significant differences between the two groups regarding LH,E_(2),and complement C4 levels(P>0.05).The clinical total effective rate in the experimental group was 86.67%(26/30),significantly higher than that in the control group,which was 43.33%(13/30)(P<0.01).Conclusion:Women with SLE of childbearing age experience decreased ovarian reserve function.The Bushen Yangrong Formula can effectively improve hormone levels,menstrual conditions,and ovarian function in these patients,thereby enhancing their quality of life.

关 键 词：抑郁症 肝郁脾虚型 调神解郁 呼吸补泻 穴位埋线 

分 类 号：R277.7[医药卫生—中医学]