老年支气管扩张合并肺部感染患者痰液病原菌培养结果及药敏试验结果分析  

Analysis of Sputum Pathogen Culture and Drug Susceptibility Test in Elderly Bronchiectasis with Pulmonary Infection

作　　者：穆艳 MU Yan(Zunyi City Bozhou District Hospital of Traditional Chinese Medicine,Zunyi 563100,China)

机构地区：[1]遵义市播州区中医院,贵州遵义563100

出　　处：《中外医学研究》2024年第25期80-83,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨老年支气管扩张合并肺部感染患者痰液病原菌培养结果及药敏试验结果。方法:选取2021年1月—2023年12月遵义市播州区中医院收治的89例老年支气管扩张合并肺部感染患者为研究对象,均采集痰液标本送检,行病原菌培养及药敏试验;统计病原菌检出情况及耐药性。结果:89例患者共分离出97株病原菌,其中革兰阴性菌检出61株(62.89%),前三为铜绿假单胞菌(29.90%)、肺炎克雷伯菌(18.56%)、大肠埃希菌(14.43%);革兰阳性菌检出32株(32.99%),前三为金黄色葡萄球菌(10.31%)、表皮葡萄球菌(8.25%)、肺炎链球菌(6.19%);真菌4株(4.12%);主要革兰阴性菌未检出对厄他培南、亚胺培南耐药菌株;其中大肠埃希菌对头孢呋辛、头孢曲松等耐药性高;主要革兰阳性菌对万古霉素、利奈唑胺、替考拉宁无耐药性,其中金黄色葡萄球菌、表皮葡萄球菌对青霉素、红霉素等耐药性高。结论:老年支气管扩张合并肺部感染患者痰液内病原菌以革兰阴性菌为主,并存在少量真菌,还需积极参照药敏结果用药,更好促进感染消失。Objective:To explore the results of sputum pathogen culture and drug susceptibility test in elderly patients with bronchiectasis combined with pulmonary infection.Method:Eighty-nine elderly patients with bronchiectasis combined with pulmonary infection admitted to Zunyi City Bozhou District Hospital of Traditional Chinese Medicine from January 2021 to December 2023 were selected as the study objects.Sputum samples were collected for examination,pathogen culture and drug susceptibility test were performed.The detection and drug resistance of pathogenic bacteria were analyzed.Result:A total of 97 strains of pathogenic bacteria were isolated from 89 patients,of which 61 strains(62.89%)were Gram-negative bacilli,the top three were Pseudomonas aeruginosa(29.90%),Klebsiella pneumoniae(18.56%)and Escherichia coli(14.43%).32 strains(32.99%)of Gram-positive cocci were detected,the top three were Staphylococcus aureus(10.31%),Staphylococcus epidermidis(8.25%)and Streptococcus pneumoniae(6.19%).Four strains(4.12%)were fungi.The main Gram-negative bacteria were not resistant to Ertapenem and Imipenem.Escherichia coli had high resistance to Cefuroxime and Ceftriaxone.The main Gram-positive bacteria had no resistance to Vancomycin,Linezolid and Teicolanin,among which Staphylococcus aureus and Staphylococcus epidermidis had high resistance to Penicillin and Erythromycin.Conclusion:The sputum pathogens in elderly patients with bronchiectasis and pulmonary infection are mainly Gram-negative bacteria,with a small amount of fungi,so drugs should actively refer to the results of drug sensitivity to better promote the disappearance of infection.

关 键 词：支气管扩张 肺部感染 病原菌培养 药敏试验 

分 类 号：R446.5[医药卫生—诊断学] R562.22[医药卫生—临床医学]