对肥胖型多囊卵巢综合征患者行生活方式干预的有效性分析  

Analysis of the effectiveness of lifestyle intervention in obese patients with polycystic ovary syndrome

作　　者：刘夏蕾 管桂雪 高原 孙倩[2] 徐金金 张琳娜 张小佐 杨文[2] LIU Xia-lei;GUAN Gui-xue;GAO Yuan(Jinzhou Medical University,Jinzhou 121001,China)

机构地区：[1]锦州医科大学,121001 [2]连云港市第一人民医院妇科,222000

出　　处：《中国实用医药》2024年第17期162-165,共4页China Practical Medicine

基　　金：连云港市妇幼保健重点人才(项目编号:FRC202003);连云港市妇幼健康科研项目(项目编号:F202103)。

摘　　要：目的探析肥胖型多囊卵巢综合征患者行生活方式干预的效果。方法70例肥胖型多囊卵巢综合征患者,利用单双号将所有患者分为对照组和观察组,每组35例。对照组行常规药物治疗,观察组在常规药物的基础上施加生活干预。对比两组患者干预前后的体重、身体质量指数(BMI)、腹围、卵巢体积、内分泌指标以及排卵率、妊娠率、月经恢复率。结果干预后,观察组患者的体重(52.17±3.95)kg、BMI(20.15±2.32)kg/m^(2)、腹围(85.61±4.69)cm均低于对照组的(57.28±3.96)kg、(22.18±2.33)kg/m^(2)、(92.65±4.71)cm(P<0.05)。干预后,观察组左卵巢体积(5.56±1.12)cm^(3)、右卵巢体积(5.42±1.11)cm^(3)低于对照组的(6.72±1.32)、(7.14±1.35)cm^(3)(P<0.05)。干预后,观察组患者睾酮(T)(2.17±0.23)nmol/L、黄体生成素(LH)(7.41±1.25)IU/L低于对照组的(3.12±0.28)nmol/L、(11.32±1.33)IU/L,卵泡刺激素(FSH)(5.13±0.65)IU/L高于对照组的(3.97±0.44)IU/L(P<0.05)。观察组排卵率、妊娠率及月经恢复率分别为77.14%、37.14%、91.43%,均高于对照组的54.29%、14.29%、68.57%(P<0.05)。结论在肥胖型多囊卵巢综合征患者中应用生活方式干预具有良好的效果,可以有效改善患者的临床症状,改善指标,提高妊娠率,促进康复,值得推广。Objective To explore the effect of lifestyle intervention in obese patients with polycystic ovary syndrome.Methods 70 cases of obese patients with polycystic ovary syndrome were divided into a control group and an observation group by odd-even number method,with 35 cases in each group.The control group was treated with conventional medication,and the observation group was treated with lifestyle intervention on the basis of conventional medication.Both groups were compared in terms of weight,body mass index(BMI),abdominal circumference,ovarian volume and endocrine indexes before and after the intervention,ovulation rate,pregnancy rate and menstrual recovery rate.Results After the intervention,in the observation group,the body weight was(52.17±3.95)kg,BMI was(20.15±2.32)kg/m^(2) and the abdominal circumference was(85.61±4.69)cm,which were lower than(57.28±3.96)kg,(22.18±2.33)kg/m^(2) and(92.65±4.71)cm in the control group(P<0.05).After the intervention,the observation group had left ovarian volume of(5.56±1.12)cm^(3)and the right ovarian volume of(5.42±1.11)cm^(3),which were lower than(6.72±1.32)and(7.14±1.35)cm^(3)in the control group P<0.05).After the intervention,the observation group had testosterone(T)of(2.17±0.23)nmol/L and luteinizing hormone(LH)of(7.41±1.25)IU/L,which were lower than(3.12±0.28)nmol/L and(11.32±1.33)IU/L in the control group;FSH of(5.13±0.65)IU/L in the observation group was higher than(3.97±0.44)IU/L in the control group(P<0.05).The ovulation rate,pregnancy rate and menstrual recovery rate in the observation group were 77.14%,37.14%and 91.43%,which were higher than 54.29%,14.29%and 68.57%in the control group(P<0.05).Conclusion The application of lifestyle intervention in obese patients with polycystic ovary syndrome has a good effect,which can effectively improve the clinical symptoms of patients,improve indicators,increase pregnancy rate,and promote rehabilitation,and is worthy of promotion.

关 键 词：多囊卵巢综合征 生活方式干预 肥胖 临床疗效 

分 类 号：R711.75[医药卫生—妇产科学]