Hypoglycaemia in screening oral glucose tolerance test in pregnancy with low birth weight fetus  

作　　者：Nicoleta Gana Iulia Huluta Nicolae Gica 

机构地区：[1]Department of Obstetrics and Gynecology,Filantropia Clinical Hospital Bucharest,Bucharest 099098,Romania [2]Department of Obstetrics and Gynecology,Carol Davila University of Medicine and Pharmacy,Bucharest 098909,Romania

出　　处：《World Journal of Experimental Medicine》2024年第3期119-121,共3页世界实验医学杂志

摘　　要：Maternal hypoglycemia,a condition characterized by lower than normal blood glucose levels in pregnant women,has been increasingly associated with adverse pregnancy outcomes,including low birth weight(LBW)in neonates.LBW,defined as a birth weight of less than 2500 g,can result from various factors,including maternal nutrition,health status,and metabolic conditions like hypoglycemia.Maternal hypoglycemia may affect fetal growth by altering the supply of essential nutrients and oxygen to the fetus,leading to restricted fetal development and growth.This condition poses significant risks not only during pregnancy but also for the long-term health of the child,increasing the likelihood of developmental delays,health issues,and chronic conditions later in life.Research in this area has focused on understanding the mechanisms through which maternal hypoglycemia influences fetal development,with studies suggesting that alterations in placental blood flow and nutrient transport,as well as direct effects on fetal insulin levels and metabolism,may play a role.Given the potential impact of maternal hypoglycemia on neonatal health outcomes,early detection and management are crucial to minimize risks for LBW and its associated complications.Further investigations are needed to fully elucidate the complex interactions between maternal glucose levels and fetal growth,as well as to develop targeted interventions to support the health of both mother and child.Understanding these relationships is vital for improving prenatal care and outcomes for pregnancies complicated by hypoglycemia.

关 键 词：Glucose tolerance test Low birth weight HYPOGLYCAEMIA High-risk pregnancy Neonatal outcome 

分 类 号：R714.5[医药卫生—妇产科学]