Indication of conservative treatment by antibiotics for uncomplicated and complicated acute appendicitis  

作　　者：Yuichi Hosokawa Masato Moritani Yosuke Makuuchi Yuichi Nagakawa 

机构地区：[1]Department of Surgery,Nishitokyo Central General Hospital,Tokyo 188-0014,Japan [2]Department of Gastrointestinal and Pediatric Surgery,Tokyo Medical University,Tokyo 166-0023,Japan

出　　处：《World Journal of Gastrointestinal Surgery》2024年第8期2538-2545,共8页世界胃肠外科杂志（英文版）（电子版）

摘　　要：BACKGROUND Acute appendicitis is one of the most common emergency abdominal disease,and recent studies have evaluated conservative treatment using antibiotics for uncomplicated appendicitis.Although the efficacy of conservative treatment for uncomplicated appendicitis is known,its efficacy for complicated appendicitis remains unknown,so are risk factors for the conservative treatment of appendi-citis.In our institution,conservative treatment has long been the first choice for most appendicitis cases,except for perforation.Therefore,this novel study inves-tigated the outcomes of conservative treatment for uncomplicated and compli-cated acute appendicitis and the risk factors associated with conservative treat-ment.treatment.The significant and independent predictors of resistance to conservative treatment were body temperature≥37.3℃,appendicolith and Douglas sinus fluid visible on computed tomography(CT).The rate of resistance to conservative treatment was 66.7%(6/9)for patients with the above three factors,22.9%(8/35)for patients with two factors(appendicolith and body temperature≥37.3℃),16.7%(2/12)for patients with two factors(Douglas sinus fluid and appendicolith)and 11.1%(1/9)for patients with two factors(Douglas sinus fluid and body temperature≥37.3℃).CONCLUSION A temperature≥37.3℃,appendicolith and Douglas sinus fluid on CT might be clinical risk factors of resistance to conservative treatment for acute appendicitis.

关 键 词：Acute appendicitis Conservative treatment ANTIBIOTICS APPENDICOLITH Uncomplicated appendicitis 

分 类 号：R726.5[医药卫生—儿科]