Pulmonary abscess caused by Streptococcus pseudopneumoniae in a child:A case report and review of literature  

作　　者：Ran Ma Yan-Mei Wang Hua Guan Li Zhang Wei Zhang Ling-Cai Chen 

机构地区：[1]Department of Pediatrics,Shihezi University,Shihezi 832000,Xinjiang Uygur Autonomous Region,China [2]Department of Pediatrics,The First Affiliated Hospital of Shihezi University,Shihezi 832000,Xinjiang Uygur Autonomous Region,China [3]Department of Pediatrics,Corps Fourth Division Hospital,Yining 844500,Xinjiang Uygur Autonomous Region,China [4]Department of Pediatrics,Corps First Division Hospital,Aksu 842008,Xinjiang Uygur Autonomous Region,China

出　　处：《World Journal of Radiology》2024年第8期362-370,共9页世界放射学杂志（英文版）（电子版）

基　　金：Supported by Corps Guiding Plan Project of Xinjiang Uygur Autonomous Region,China,No.2022ZD031;Financial Science and Technology Plan Project of Shihezi,Xinjiang Uygur Autonomous Region of China,No.2022NY01;Research Project of Shihezi University of Shihezi,Xinjiang Uygur Autonomous Region of China,No.ZZZC202072A.

摘　　要：BACKGROUND Lung abscess found on chest X-ray and computed tomography examinations is rare in infants and young children.Several pathogens can cause lung abscesses,with the most common pathogens being anaerobes,Streptococci and Staphylococcus aureus.Streptococcus pseudopneumoniae(S.pseudopneumoniae)is a member of the Streptococcaceae family,and is mainly isolated from respiratory tract specimens.There are currently no cases of lung abscess caused by S.pseudopneumoniae in the literature.CASE SUMMARY A 2-year-old boy was admitted to hospital due to persistent cough and fever.Lung computed tomography examination suggested the formation of a lung abscess.His diagnosis was not confirmed by testing for serum respiratory pathogens(6 items),respiratory pathogen nucleic acid(27 items),and laboratory culture.Finally,metagenomic next-generation sequencing of bronchoalveolar lavage fluid revealed the presence of S.pseudopneumoniae,confirming its role in causing the lung abscess.After receiving antibiotic treatment,reexamination with lung computed tomography showed that the abscess was resorbed and the patient’s outcome was good.CONCLUSION This is the first report of a lung abscess in a child caused by S.pseudopneumoniae infection.Metagenomic next-generation sequencing of bronchoalveolar lavage fluid is helpful in achieving rapid and accurate pathogen identification.

关 键 词：Streptococcus pseudopneumoniae Lung abscess Children Bronchoalveolar lavage fluid Metagenomic nextgeneration sequencing Case report 

分 类 号：R563.1[医药卫生—呼吸系统]